Results 31 to 40 of about 3,755,672 (209)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Temperature

open access: yes, 2018
This file contains minimum temperature, maximum temperature, and average temperature, and growing degree day data for every day of the study ...
Anderson, Jill T.   +9 more
core   +1 more source

TEMPERATURE

open access: yesAnnals of the Academy of Romanian Scientists Series on Mathematics and Its Application
Conversations about weather, environment, health, cuisine, and even politics all involve the word ”temperature”. It was an attempt to understand the working of the heat engines that gave the temperature a clear definition. In this paper, we put the equilibrium thermodynamics definition into a larger context of multiscale thermodynamics, the multiscale ...
openaire   +2 more sources

Monitoring temperature [PDF]

open access: yesBritish Journal of Nursing, 2019
This article explains the importance of temperature monitoring observations and highlights that the procedure is a fundamental aspect of nursing care. It discusses the physiology of temperature regulation, introduces different types of temperature monitoring devices and provides a step-by-step guide on how to take a temperature using a tympanic ...
Robertson, Matthew, Hill, Barry
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Dynamically Self-Validating Contact Temperature Sensors

open access: yes, 2020
. Thermocouple and RTD technology is the workhorse of the temperature measurement industry. It has been refined and extended to cover a broad range of temperature measurement needs. However, it is well documented, though not widely advertised, that these
-Isa Temperature Reprint   +2 more
core  

Temperature observations from northernmost Greenland, 2006-2010 [PDF]

open access: yes, 2017
Air-, surface-, and subsurface temperatures were recorded by automatic weather stations in Bliss Bugt and Moore Gletscher, Johannes V. Jensen Land, North coast of Greenland from 2006-2010. The mean annual surface temperature is -12.1 ℃ in Bliss Bugt and -
Larsen, Nicolaj K.   +5 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy