Results 51 to 60 of about 11,188,735 (300)

O'KKLT at Finite Temperature

open access: yes, 2008
We study whether finite temperature corrections decompactify the internal space in KKLT compactifications with an uplifting sector given by a system that exhibits metastable dynamical supersymmetry breaking.
Abe   +63 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Temperature invariant metasurfaces

open access: yesHigh Contrast Metastructures XII, 2023
Abstract Thermal effects are well known to influence the electronic and optical properties of materials through several physical mechanisms and are the basis for various optoelectronic devices. The thermo-optic (TO) effect, the refractive index variation with temperature (dn/dT), is one of the most common mechanisms used for tunable ...
Shany Zrihan Cohen   +3 more
openaire   +4 more sources

Sphalerons at finite temperature

open access: yes, 1993
We construct the sphaleron for several temperature dependent effective potentials. We determine the sphaleron energy as a function of temperature and demonstrate that the sphaleron energy at a given temperature $T$ is well approximated by the sphaleron ...
Braibant, Sylvie   +2 more
core   +1 more source

Temperature-sensitive protein–DNA dimerizers [PDF]

open access: yes, 2005
Programmable DNA-binding polyamides coupled to short peptides have led to the creation of synthetic artificial transcription factors. A hairpin polyamide-YPWM tetrapeptide conjugate facilitates the binding of a natural transcription factor Exd to an ...
Ansari, Aseem Z.   +6 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A compound-specific method for measuring the stable carbon isotopic composition of amino acids: elimination of the effect of isotopic fractionation during derivatization

open access: yesProgress in Earth and Planetary Science
Compound-specific isotope analysis (CSIA) of carbon and nitrogen within amino acids by gas chromatography/isotope ratio mass spectrometry (GC/IRMS) has been employed as a powerful tool for estimating the trophic tendency and resource utilization of ...
Yoshito Chikaraishi   +3 more
doaj   +1 more source

Quantum mechanisms for selective detection in complex gas mixtures using conductive sensors

open access: yesScientific Reports, 2023
In this paper, we consider new quantum mechanisms for selective detection in complex gaseous media which provide the highest possible efficiency of quantum sensors and for the first time analyze their nature. On the basis of these quantum mechanisms, the
G. Kamarchuk   +9 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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