Results 41 to 50 of about 3,797,276 (269)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A compound-specific method for measuring the stable carbon isotopic composition of amino acids: elimination of the effect of isotopic fractionation during derivatization

Progress in Earth and Planetary Science
Compound-specific isotope analysis (CSIA) of carbon and nitrogen within amino acids by gas chromatography/isotope ratio mass spectrometry (GC/IRMS) has been employed as a powerful tool for estimating the trophic tendency and resource utilization of ...
Yoshito Chikaraishi, Hyuntae Choi, Nayeon Park, Yuko Takizawa   +3 more
doaj   +1 more source

Quantum mechanisms for selective detection in complex gas mixtures using conductive sensors

Scientific Reports, 2023
In this paper, we consider new quantum mechanisms for selective detection in complex gaseous media which provide the highest possible efficiency of quantum sensors and for the first time analyze their nature. On the basis of these quantum mechanisms, the
G. Kamarchuk, A. Pospelov, L. Kamarchuk, V. Belan, A. Herus, A. Savytskyi, V. Vakula, D. Harbuz, V. Gudimenko, E. Faulques   +9 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Rate-Determining Steps of Oxygen Surface Exchange Kinetics on Sr₂Fe_1.5Mo_0.5O_6−δ

Energies, 2020
The oxygen surface kinetics of Sr2Fe1.5Mo0.5O6−δ was determined using the 16O2/18O2 isotope exchange method with gas phase analysis at 600−800 °C.
Denis A. Osinkin, Anna V. Khodimchuk, Natalia M. Porotnikova, Nina M. Bogdanovich, Andrey V. Fetisov, Maxim V. Ananyev   +5 more
doaj   +1 more source

A CONSTANT TEMPERATURE BATH FOR LOW TEMPERATURES. [PDF]

Journal of the American Chemical Society, 1905
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openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Sensing temperature [PDF]

Current Biology, 2013
Temperature is an omnipresent physical variable reflecting the rotational, vibrational and translational motion of matter, what Richard Feynman called the "jiggling" of atoms. Temperature varies across space and time, and this variation has dramatic effects on the physiology of living cells.
Sengupta, Piali, Garrity, Paul
openaire   +2 more sources