Results 81 to 90 of about 18,071,019 (382)
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Standards in Genomic Sciences, 2017 Desulfoplanes formicivorans strain Pf12BT is the type strain of the type species in the genus Desulfoplanes, which is the one of the genera in the family Desulfomicrobiaceae within the order Desulfovibrionales. This deltaproteobacterium was isolated from
Miho Watanabe +2 more
doaj +1 more source
Current Biology, 2013 Temperature is an omnipresent physical variable reflecting the rotational, vibrational and translational motion of matter, what Richard Feynman called the "jiggling" of atoms. Temperature varies across space and time, and this variation has dramatic effects on the physiology of living cells.
Sengupta, Piali, Garrity, Paul
openaire +2 more sources
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Synthesis and electrical properties of doped layered perovskites based on BaMInO4 (M = Y, Gd)
Chimica Techno ActaPerovskite or perovskite-related structural materials are widely studied for their many functional properties. They can be used as components of electrochemical devices such as solid oxide fuel cells and electrolyzers.
Nataliia Tarasova +5 more
doaj +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Metamagnetic transition in single-crystalline UIr $$_{2}$$ 2 Si $$_{2}$$ 2
Scientific Reports, 2023 A single crystal of the ternary uranium silicide UIr $$_{2}$$ 2 Si $$_{2}$$ 2 was studied by means of of X-ray diffraction, magnetization, heat capacity and electrical transport measurements.
Maria Szlawska +3 more
doaj +1 more source
Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution
FEBS Letters, EarlyView.The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai +2 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source