Results 101 to 110 of about 10,051,843 (305)
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Improving Thermal Performance in Data Centers Based on Numerical Simulations
Buildings(1) Background: With the rapid development of cloud computing, large AI models, and other emerging technologies, the issue of heat dissipation in data centers has become increasingly prominent.
Yinjie Guo +4 more
doaj +1 more source
, 2005 Different types of boundary conditions for temperature (Dirichlet, Neumann, mixed and some others) at the base of a heap comprising oxidizable material are numerically examined for their influence on temperature distribution and overall heat content ...
Stepanyants, Yury, Crawford, Jagoda
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Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Estimating temperature distribution and heat quantity of spindle shaft for machining centers
Journal of Advanced Mechanical Design, Systems, and ManufacturingThe thermal issue of spindles for machining centers is still fundamentally unresolved. Thermal problems due to increased temperature of the spindle shaft lead to thermal displacement of the tool axis and an increase in friction torque, consequently ...
Shingo KAJIKAWA +3 more
doaj +1 more source
An Essay on the Philosophy and Psychodynamics of Income Distribution
, 1992 This essay considers certain fundamental aspects of the philosophy and psychodynamics of distribution and how they have entered economic theory. It treats, first, considerations of distribution as a driving force in the economy; second, the forces and ...
Samuels, W. J.
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FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
The Beaman Distribution: A New Descriptive Model for the Size Distribution of Incomes
, 2008 A new two-parameter descriptive model for the size distribution of incomes is presented. The Beaman distribution, originally found to describe the relationship between prices and sales volumes of textiles and related products, is shown to fit closely US ...
Maclachlan, Fiona C., Reith, John E.
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