Results 101 to 110 of about 1,857,057 (316)

Evaporator for thermal deposition of materials in vacuum

open access: yesТехнологія та конструювання в електронній апаратурі, 2008
The design of an evaporator intended for material deposition in vacuum-coating systems is considered, which has been successfully employed in the technological process of fabricating gallium arsenide transistors, diodes, and monolithic circuits.
V. I. Bosyi   +2 more
doaj  

Numerical Investigations of the Thermal State of Overhead Lines and Underground Cables in Distribution Networks [PDF]

open access: yes, 2011
As part of extensive activities on the reduction of CO2 emissions, a rapid expansion of power generation using new more fuel efficient technologies (large, medium and embedded scale with combined heat and power (CHP) projects) and renewable energy ...
MAKHKAMOVA, IRINA
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Research on Annular Pressure Buildup in Deepwater Oil and Gas Well

open access: yesShiyou jixie, 2018
The annulus pressure buildup of deepwater oil and gas wells refers to the phenomenon that the casing annulus fluid expands, owing to the temperature increase, to cause the closed space to generate additional pressure.
Wu Xueting, Wang Jiangshuai, Feng Wei
doaj  

Low-temperature cooling behavior of single-domain magnetite: Forcing of the crystallographic axes and interactions [PDF]

open access: yes, 2006
Low-temperature cycling (LTC) of magnetic remanences carried by rocks has become a standard technique in paleomagnetism, rock magnetism, and environmental magnetism as a means of identifying mineralogy and grain size.
Williams, Wyn; id_orcid
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Temperature-driven biogeography of the deep-sea family Lithodidae (Crustacea: Decapoda: Anomura) in the Southern Ocean

open access: yes, 2010
Species’ distributions are dynamic and are linked to the changing physical environment. Temperature is considered to be a major factor influencing biogeography, especially in ectotherms such as the family Lithodidae.
Thatje, S.   +3 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

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