Results 81 to 90 of about 10,051,843 (305)
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Thermal-breaking characteristics and crack distribution of rock irradiated by laser beams
Yantu gongcheng xuebaoThe laser-assisted rock breaking is a non-contact technology employed for the rock fragmentation, with its efficiency contingent upon the laser power, irradiation time and defocusing distance. To explore the effects of various irradiation parameters, the
WANG Yijiang 1, 2, 3, YU Dongxu 1, SUN Lipeng 1, ZHU Qiyin 2, 3, WANG Jianzhou 2, 3
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Kongzhi Yu Xinxi JishuIn order to investigate the reaction characteristics of 25 Ah and 50 Ah lithium iron phosphate (LiFePO4) cells at 100% state of charge (SOC) under the thermal runaway state and to examine the spreading patterns of smoke during the thermal runaway ...
LIU Li +5 more
doaj
Space Charge Formation and its Modified Electric Field under Applied Voltage Reversal and Temperature Gradient in XLPE Cable [PDF]
, 2008 The results of space charge evolution in cross-linked polyethylene power cables under dc electrical field at a uniform temperature and during external voltage polarity reversal are presented in the paper.
Fu, Mingli +11 more
core +1 more source
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Evaporator for thermal deposition of materials in vacuum
Технологія та конструювання в електронній апаратурі, 2008 The design of an evaporator intended for material deposition in vacuum-coating systems is considered, which has been successfully employed in the technological process of fabricating gallium arsenide transistors, diodes, and monolithic circuits.
V. I. Bosyi +2 more
doaj
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Temperature distribution at steady state.
, 2015 Temperature distribution at steady state.
Liwei Li (804248) +4 more
core +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Molecular Oncology, EarlyView.Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source