Results 71 to 80 of about 1,623,204 (266)
Energies, 2020 The impact of micro porous layer (MPL) with various thicknesses of polymer electrolyte membrane (PEM) on heat and mass transfer characteristics, as well as power generation performance of Polymer Electrolyte Fuel Cell (PEFC), is investigated.
Akira Nishimura +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Thermal-breaking characteristics and crack distribution of rock irradiated by laser beams
Yantu gongcheng xuebaoThe laser-assisted rock breaking is a non-contact technology employed for the rock fragmentation, with its efficiency contingent upon the laser power, irradiation time and defocusing distance. To explore the effects of various irradiation parameters, the
WANG Yijiang 1, 2, 3, YU Dongxu 1, SUN Lipeng 1, ZHU Qiyin 2, 3, WANG Jianzhou 2, 3
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Kongzhi Yu Xinxi JishuIn order to investigate the reaction characteristics of 25 Ah and 50 Ah lithium iron phosphate (LiFePO4) cells at 100% state of charge (SOC) under the thermal runaway state and to examine the spreading patterns of smoke during the thermal runaway ...
LIU Li +5 more
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Evaporator for thermal deposition of materials in vacuum
Технологія та конструювання в електронній апаратурі, 2008 The design of an evaporator intended for material deposition in vacuum-coating systems is considered, which has been successfully employed in the technological process of fabricating gallium arsenide transistors, diodes, and monolithic circuits.
V. I. Bosyi +2 more
doaj
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source