Results 71 to 80 of about 3,130,753 (313)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Surfactant and temperature effects on paraben transport through silicone membranes
, 2013 This study investigates the effects of two surfactants (one anionic and one non-ionic) and controlled modifications in temperature (298–323 K) on the permeation of two structurally similar compounds through a silicone membrane using a Franz diffusion ...
Bibi, Aisha +3 more
core +1 more source
علوم آب و خاک, 2019 Alginate biopolymer, due to possessing a high capacity and affinity for heavy metals, is a suitable material for the removal of metals from polluted waters; however, the weak structural consistency of alginate hydogels limits the practical application of
N. Zough, M. Shirvani
doaj
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Temperature sensitivity of soil carbon decomposition [PDF]
, 2013 The world's soils contain three times as much carbon as the atmosphere. Thus, any changes in this carbon pool may affect atmospheric CO₂ levels with implications for climate change.
Erhagen, Björn
core
Modelling the effect of temperature on the development of Polymyxa betae
, 2000 Polymyxa betae is the fungal vector of beet necrotic yellow vein virus (BNYVV), which is the causal agent of the sugar beet disease rhizomania. The within-season dynamics of the fungus are a crucial factor in the occurrence and severity of rhizomania ...
Webb, C. R. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Meikuang AnquanIn order to study the consolidation bearing capacity of coal-based solid waste paste backfill in deep high ground temperature environment of coal mine, uniaxial compression and acoustic emission tests were used to test the strength and failure ...
Zhiqiang WEN +4 more
doaj +1 more source
Few-Layer Graphene-Based Nanofluids with Enhanced Thermal Conductivity
Nanomaterials, 2020 High-quality graphene is an especially promising carbon nanomaterial for developing nanofluids for enhancing heat transfer in fluid circulation systems. We report a complete study on few layer graphene (FLG) based nanofluids, including FLG synthesis, FLG-
Samah Hamze +10 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source