Results 81 to 90 of about 15,716,870 (262)
Temperature sensitivity of soil carbon decomposition [PDF]
, 2013 The world's soils contain three times as much carbon as the atmosphere. Thus, any changes in this carbon pool may affect atmospheric CO₂ levels with implications for climate change.
Erhagen, Björn
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
SensorsMetal-μhemispherical resonant gyros (M-μHRGs) are widely used in highly dynamic navigation systems in extreme environments due to their high accuracy and structural stability.
Xiangxian Yao +4 more
doaj +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Frontiers in MicrobiologyInsect population control using pesticides faces new challenges as global temperatures change. Symbiotic bacteria of insects play a key role in insect resistance to pesticides, and these symbiotic bacteria themselves are sensitive to the effects of ...
Mengxin Ma +16 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Mechanical properties of boron nitride sheet with randomly distributed vacancy defects
Nanotechnology Reviews, 2019 Defects and temperature effects on the mechanical properties of hexagonal boron nitride sheet (h-BN) containing randomly distributed defects are investigated by molecular dynamics simulations and the reasons of the results are discussed.
Liang Yingjing +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Effect of pouring temperature on thixotropic microstructure formation of AZ91
, 2007 The effect of pouring temperature on thixotropic microstructure of AZ91 was investigated. The results show that the pouring temperature has a pronounced effect both on microstructural morphology and grain size.
Ning, Zhiliang +4 more
core