Results 101 to 110 of about 18,906,331 (342)

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Non-isothermal mathematical model of blocking tecnogenic fractures

Вестник Самарского университета: Естественнонаучная серия
Nowadays, large oil fields have moved to the stage of declining production, to maintain reservoir pressure, it is necessary to apply flooding technologies.
Anton M. Kasperovich, Alexander P. Shevelev, Alexander Y. Gilmanov   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Low Temperature Properties of the Random Field Potts Chain

, 2002
The random field q-States Potts model is investigated using exact groundstates and finite-temperature transfer matrix calculations. It is found that the domain structure and the Zeeman energy of the domains resembles for general q the random field Ising ...
Alava, Mikko, Paul, Raja, Rieger, Heiko
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Influence of track line environment on the temperature field of a double-block ballastless track slab

Advances in Mechanical Engineering, 2018
The heat flux density of solar radiation, received by each surface of a double-block ballastless track bed slab, is closely related to its alignment and geographical latitude.
Z. Zeng, Zhibin Huang, Hua-tuo Yin, Xiaobai Meng, Weidong Wang, Jundong Wang   +5 more
semanticscholar   +1 more source

Gauge--invariant field correlators in QCD at finite temperature

, 1996
We study by numerical simulations on a lattice the behaviour of the gauge--invariant two--point correlation functions of the gauge field strengths across the deconfinement phase transition.Comment: 12 pages, LaTeX file, + 5 PS figures, uuencoded-tar ...
A. Di Giacomo, Bali, Campostrini, Campostrini, Campostrini, Di Giacomo, Di Giacomo, Di Giacomo, Dosch, Dosch, Dosch, E. Meggiolaro, Gromes, H. Panagopoulos, Krämer, Laermann, Landshoff, Michael, Nachtmann, Simonov, Simonov, Simonov, Simonov, Simonov, Simonov   +24 more
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Implementation of a Digital Model of Thermal Characteristics Based on the Temperature Field

Advanced Engineering Research
Introduction. Computer modeling allows engineers to make valid design decisions by accurately assessing the thermal characteristics of design objects. The implementation of digital twin technology in the process of designing technical facilities is the ...
V. V. Pozevalkin, A. N. Polyakov
doaj   +1 more source

Analytical solution and numerical simulation of the liquid nitrogen freezing-temperature field of a single pipe

, 2018
Artificial liquid nitrogen freezing technology is widely used in urban underground engineering due to its technical advantages, such as simple freezing system, high freezing speed, low freezing temperature, high strength of frozen soil, and absence of ...
Cai Haibing, Liuxun Xu, Yugui Yang, Long-qi Li   +3 more
semanticscholar   +1 more source