Results 101 to 110 of about 13,706,361 (339)

Upper temperature limits of tropical marine ectotherms: global warming implications [PDF]

open access: yes, 2011
Animal physiology, ecology and evolution are affected by temperature and it is expected that community structure will be strongly influenced by global warming.
Peck, Lloyd S.   +27 more
core   +2 more sources

Study of a temperature gradient metamorphism of snow from 3-D images: time evolution of microstructures, physical properties and their associated anisotropy

open access: yes, 2014
We carried out a study to monitor the time evolution of microstructural and physical properties of snow during temperature gradient metamorphism: a snow slab was subjected to a constant temperature gradient in the vertical direction for 3 weeks in a cold
N. Calonne   +4 more
semanticscholar   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Biomimetic Gradient Porous Core–Shell Fibers with Enhanced Gas Sensing for CO‑Temperature Dual‑Mode Early Fire Warning

open access: yes
Early fire detection systems that are highly sensitive are essential for reducing the impact of fire disasters. However, their development still faces significant challenges due to the lack of capability for simultaneous monitoring of both temperature ...
Mia, Md Hasib   +9 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Initial Value Problem of the Toroidal Ion Temperature Gradient Mode

open access: yes, 1998
"The initial value problem of the toroidal ion temperature gradient mode is studied based on the Laplace transform of the ion gyrokinetic equation and the electron Boltzmann relation with the charge neutrality condition.
Okamoto, M.   +4 more
core  

Nonlinear cross Gramians and gradient systems [PDF]

open access: yes, 2007
We study the notion of cross Gramians for non-linear gradient systems, using the characterization in terms of prolongation and gradient extension associated to the system.
Jacquelien M. A. Scherpen   +5 more
core   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Demonstrating the Temperature Gradient Impact on Grain Growth in UO2 Using the Phase Field Method

open access: yes, 2014
Grain boundaries (GBs) are driven to migrate up a temperature gradient. In this work, we use a phase field model to investigate the impact of temperature gradients on isotropic grain growth.
M. Tonks   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy