Results 51 to 60 of about 849,151 (266)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Daytime Temperature Profiles

Journal of the Atmospheric Sciences, 1966
Abstract An equation for the daytime lapse rate of temperature as a function of z/L is derived assuming the lapse rate varies as z−⅔ in very light winds. This variation is presumed to result from the geometry of buoyant plumes. The equation, which agrees very well with some data taken by Dyer, predicts a maximum value for the lapse rate at a fixed ...
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Real-time Monitoring of Oil-well Dynamic Liquid-level with Pressure and Temperature Based on Optical Fiber Sensor

Journal of Harbin University of Science and Technology, 2018
Real.time monitoring of dynamic liquid level of oil well is very important in oilfield. A novel method combining pressure measurement and temperature profile measurement is proposed in this paper to measure dynamic liquid.level of oil.well in real.time ...
ZHANG Hong-tao, FU Wei, WANG Chun-qian, ZHANG Guang-yu, WANG Zhen-long   +4 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Data-Driven Soft Sensors in Refining Processes – Pulp Property Estimation Using ARX - Models

BioResources, 2023
This paper focuses on estimation of shives(wide) and fiber length in RGP82CD-refiners using an AutoRegressive eXogenous (ARX) structure in a data-driven soft sensor concept. Both external and internal variables are considered as model inputs.
Anders Karlström, Jan Hill, Lars Johansson   +2 more
doaj   +2 more sources

Modeling and Design of a Multi-Tubular Packed-Bed Reactor for Methanol Steam Reforming over a Cu/ZnO/Al₂O₃ Catalyst

Energies, 2020
Methanol as a hydrogen carrier can be reformed with steam over Cu/ZnO/Al2O3 catalysts. In this paper a comprehensive pseudo-homogenous model of a multi-tubular packed-bed reformer has been developed to investigate the impact of operating conditions and ...
Jimin Zhu, Samuel Simon Araya, Xiaoti Cui, Simon Lennart Sahlin, Søren Knudsen Kær   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Temperature-dependent density profiles of dipolar droplets [PDF]

Physical Review A, 2019
Recently, trapped dipolar gases were observed to form high density droplets in a regime where mean field theory predicts collapse. These droplets present a novel form of equilibrium where quantum fluctuations are critical for stability. So far, the effect of quantum fluctuations have only been considered at zero temperature through the local chemical ...
Aybar, E., Oktel, M. O.
openaire   +4 more sources