Results 91 to 100 of about 1,799,197 (305)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Reversal-free CaIIH profiles: a challenge for solar chromosphere modeling in quiet inter-network

, 2008
We study chromospheric emission to understand the temperature stratification in the solar chromosphere. We observed the intensity profile of the CaIIH line in a quiet Sun region close to the disk center at the German Vacuum Tower Telescope.
Avrett, Ayres, Ayres, Balasubramaniam, Beck, Beck, C. Beck, Carlsson, Carlsson, Cram, Fontenla, Fontenla, Grossman-Doerth, Heasley, Holweger, J. H. M. J. Bruls, Judge, Kalkofen, Linsky, Lites, Lites, R. Rezaei, R. Schlichenmaier, Rammacher, Rezaei, Rezaei, Schmidt, Shine, Solanki, Stenflo, Uitenbroek, Uitenbroek, Uitenbroek, Vernazza, W. Kalkofen, W. Schmidt, Wedemeyer-Böhm, Wedemeyer-Böhm, Wöger   +38 more
core   +1 more source

Temperature profiles combined from lidar and airglow measurements [PDF]

Atmospheric Measurement Techniques
In this study we examine the performance of the 354.8 nm Rayleigh temperature channel of the Raman lidar at the Schneefernerhaus high-altitude research station (UFS) in the Bavarian Alps (at 2675 m a.s.l.).
T. Trickl, H. Vogelmann, M. Bittner, M. Bittner, G. Nedoluha, C. Schmidt, W. Steinbrecht, S. Wüst   +7 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Effect of Gravity and Confinement on Phase Equilibria: A Density Matrix Renormalization Approach

, 1997
The phase diagram of the 2D Ising model confined between two infinite walls and subject to opposing surface fields and to a bulk "gravitational" field is calculated by means of density matrix renormalization methods.
A. Maciołek, A. O. Parry, A. O. Parry, Andrzej Drzewiński, D. B. Abraham, D. M. Kroll, E. V. Albano, E. V. Albano, Enrico Carlon, H. Au-Yang, H. Nakanishi, J. M. J. van Leeuwen, J. Rogiers, K. Binder, K. Binder, M. E. Fisher, M. E. Fisher, S. R. White, S. R. White, T. Kerle, T. Nishino   +20 more
core   +1 more source

Predicting vasovagal reactions to needles with anticipatory facial temperature profiles. [PDF]

Sci Rep, 2023
Rudokaite J, Ong LLS, Onal Ertugrul I, Janssen MP, Huis In 't Veld EMJ.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Temperature profiles in high gradient furnaces [PDF]

Accurate temperature measurement of the furnace environment is very important in both the science and technology of crystal growth as well as many other materials processing operations.
Berry, R., Crouch, R. K., Debnam, W. J., Fripp, A. L., Sorokach, S. K., Woodell, G. A.   +5 more
core   +1 more source

Measurement of temperature profiles in hot gases and flames [PDF]

, 1974
Computer program was written for calculation of molecular radiative transfer from hot gases. Shape of temperature profile was approximated in terms of simple geometric forms so profile could be characterized in terms of few parameters.
Arnold, C. B., Lindquist, G. H., Simmons, R. S., Yamada, H. Y.   +3 more
core   +1 more source