Results 81 to 90 of about 1,799,197 (305)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Experimental Study on the Reaction of Magnesium in Carbon Dioxide and Nitrogen Atmosphere

ChemEngineering
This manuscript presents an experimental study focusing on the combustion of magnesium in an atmosphere depleted of oxygen. The study explores various mixtures of carbon dioxide and nitrogen, examining their impact on the combustion performance.
Ioan Barabulica, Marius Sebastian Secula, Adriana Mariana Asoltanei, Eugenia Teodora Iacob-Tudose, Gabriela Lisa, Ioan Mamaliga   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Spatial distribution of Far infrared emission in spiral galaxies II. Heating sources and gas-to-dust ratio

, 1997
We study the radial distribution of the temperature of the warm dust and gas-to-dust mass ratios in a sample of 22 spiral galaxies. The heating capabilities of the diffuse interstellar radiation field (ISRF), based on Desert et al.
Mayya, Y. D., Rengarajan, T. N.
core   +2 more sources

X-ray spectral study of the hot gas in three Clusters of Galaxies [PDF]

, 2010
We study the physical properties of three clusters of galaxies, selected from a BeppoSAX Wide Field Camera (WFC) survey. These sources are identified as 1RXS J153934.7-833535, 1RXS J160147.6-754507, and 1RXS J081232.3-571423 in the ROSAT All-Sky Survey ...
Arnaud, Blanton, Boella, Bradt, Byram, Böhringer, Cash, Cavagnolo, Cavaliere, David, De Grandi, de Plaa, de Plaa, Dickey, E. Costantini, Ebeling, Elvis, F. Verbunt, F. Verrecchia, Gómez, Hertz, J. de Plaa, J. J. M. in 't Zand, J. S. Kaastra, Jager, Kaastra, Kaastra, Kalberla, Kellogg, Kuntz, Leccardi, Lodders, McNamara, McNamara, Mewe, Peterson, Peterson, Raymond, Reiprich, Revnivtsev, Strüder, Tamura, Tamura, Verrecchia, Voges, Werner, Wood, Wright, Y. G. Grange   +48 more
core   +1 more source

Temperature profiles of impacts [PDF]

, 1997
Similarity solutions determine the profiles of density and temperature from impacts, which determine the scaling of the temperature and optical depth on material parameters, time, screening, and impactor size. This note uses scaling results derived earlier for the growth, size, and temperature produced by impacts to discuss the radial temperature ...
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Effect of particle size and humidity on sugarcane bagasse combustion in a fixed bed furnace

Revista Ion, 2013
The panela industry is one of the most important Agro Industries in Colombia, making it the largest per- capita consumer and the second largest producer worldwide.
Zamir Sánchez Castro, Paola Gauthier-Maradei, Humberto Escalan te Hernández   +2 more
doaj  

Inverse Problem Protocol to Estimate Horizontal Groundwater Velocity from Temperature–Depth Profiles in a 2D Aquifer

Applied Sciences
A general and precise protocol that follows the standards of an inverse problem in engineering is proposed to estimate groundwater velocity from experimental lectures of temperature vertical profiles in a 2D aquifer.
Francisco Alhama, José Antonio Jiménez-Valera, Iván Alhama   +2 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source