Results 71 to 80 of about 1,799,197 (305)

Tropospheric profiles of wet refractivity and humidity from the combination of remote sensing data sets and measurements on the ground [PDF]

Atmospheric Measurement Techniques, 2013
We reconstruct atmospheric wet refractivity profiles for the western part of Switzerland with a least-squares collocation approach from data sets of (a) zenith path delays that are a byproduct of the GPS (global positioning system ...
F. Hurter, O. Maier
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Use of Radio Occultation to Evaluate Atmospheric Temperature Data from Spaceborne Infrared Sensors

Terrestrial, Atmospheric and Oceanic Sciences, 2009
With its high accuracy, stability, and worldwide coverage GPS radio occultation offers an attractive means of independently validating and calibrating the world's premier weather and climate sensors.
Thomas P. Yunck, Eric J. Fetzer, Anthony M. Mannucci, Chi O. Ao, F. William Irion, Brian D. Wilson, Gerald John M. Manipon   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Temperature-dependent density profiles of dipolar droplets [PDF]

Physical Review A, 2019
Recently, trapped dipolar gases were observed to form high density droplets in a regime where mean field theory predicts collapse. These droplets present a novel form of equilibrium where quantum fluctuations are critical for stability. So far, the effect of quantum fluctuations have only been considered at zero temperature through the local chemical ...
Aybar, E., Oktel, M. O.
openaire   +4 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Electrical power dissipation in carbon nanotubes on single crystal quartz and amorphous SiO2

, 2011
Heat dissipation in electrically biased semiconducting carbon nanotubes (CNTs) on single crystal quartz and amorphous SiO2 is examined with temperature profiles obtained by spatially resolved Raman spectroscopy.
Liao, Albert, Pop, Eric, Shim, Moonsub, Tsai, Cheng-Lin   +3 more
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Probing the dark matter profile of hot clusters and the M-T relation with XMM-Newton

, 2005
We present results based on XMM-Newton observations of a small sample of hot galaxy clusters. Making a full use of XMM-Newton's spectro-imaging capabilities, we have extracted the radial temperature profile and gas density profile, and with this ...
Allen, Arnaud, Chen, E. Pointecouteau, Evrard, Finoguenov, G.W. Pratt, M. Arnaud, Moore, Navarro, Nevalainen, Pointecouteau, Pratt, Pratt, Pratt, Sanderson   +15 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source