Results 51 to 60 of about 1,799,197 (305)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Microstability analysis of pellet fuelled discharges in MAST
Reactor grade plasmas are likely to be fuelled by pellet injection. This technique transiently perturbs the profiles, driving the density profile hollow and flattening the edge temperature profile.
Dickinson, D. +9 more
core +1 more source
The goal of this contribution is to present the latest developments performed with the VHF wind profiler at the Centre National de Recherches Météorologiques (CNRM) in Toulouse. The current work includes a radio acoustic sounding system (RASS) capability
Vladislav Klaus +5 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Degradation of road tested automotive connectors
The automotive environment is particularly demanding on connector performance, and is characterized by large temperature changes, high humidity and corrosive atmospheres.
Maul, C., McBride, J.W., Swingler, J.
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ocean Temperature Profiling Lidar: Analysis of Technology and Potential for Rapid Ocean Observations
Development of ocean measurement technologies can improve monitoring of the global Ocean Heat Content (OHC) and Heat Storage Rate (HSR) that serve as early-warning indices for climate-critical circulation processes such as the Atlantic Meridional ...
John R. Moisan +4 more
doaj +1 more source
Temperature profiles with bi-static Doppler-RASS and their correction [PDF]
The technique of atmospheric temperature profiling by Doppler-RASS is discussed. The set up with bi-static (separated transmit and receiving) antennas implies a range dependent scattering angle.
B. Hennemuth, G. Peters, H.-J. Kirtzel
doaj +1 more source
Heat transfer model verification for thermal monitoring system of integral bridges
Thermal actions considered on abutments of integral bridges by the European standard (Eurocode 1) might be in variety of certain situations underestimated. Based on this assumption, thermal monitoring system has been designed and installed into structure
Martin Jonáš, Jan Zatloukal
doaj +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source

