Results 101 to 110 of about 1,782,060 (305)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Comparison of Atmospheric Boundary Layer Height Inversion Methods over Typical Areas of the Loess Plateau

Gaoyuan qixiang
The atmospheric boundary layer height （ABLH） is one of the most important parameters in the study of atmospheric environment， weather and climate.With the development of ground-based remote sensing technology， continuous monitoring of ABLH has become ...
Xiang ZHANG, Ye YU, Longxiang DONG, Guo ZHAO, Teng MA, Shaofeng QI, Suping ZHAO, Jianglin LI, Tong ZHANG   +8 more
doaj   +1 more source

Associations between Surface and Rectal Temperature Profiles of Low-Birth-Weight Piglets. [PDF]

Animals (Basel), 2023
Tucker BS, Petrovski KR, Craig JR, Morrison RS, Smits RJ, Kirkwood RN.   +5 more
europepmc   +1 more source

Swirl-can combustor segment [PDF]

, 1970
Combustor produces uniform circumferential and radial combustor exit temperature profiles and high combustion efficiency at high temperature loads. Absence of diluent air entry ports eliminates stress concentration points, low pressure fuel alleviates ...
Jones, R., Moyer, H., Niedzwiecki, R.
core   +1 more source

Heating of the magnetic chromosphere: observational constraints from Ca II 8542 spectra

, 2013
The heating of the Sun's chromosphere remains poorly understood. While progress has been made on understanding what drives the quiet Sun internetwork chromosphere, chromospheric heating in strong magnetic field regions continues to present a difficult ...
Carlsson, M., De Pontieu, B., Rodríguez, J. de la Cruz, van der Voort, L. H. M. Rouppe   +3 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Temperature profiles of field-aged photovoltaic modules affected by optical degradation. [PDF]

Heliyon, 2023
Segbefia OK.
europepmc   +1 more source

Low level temperature profile from screen temperature

MAUSAM, 1979
A simple mathematical model for vertical temperature profile during clear and calm night time inversions, utilising screen air temperature data is presented. The model was tested at Delhi and Mathura and found to be reasonably good for pollution studies in the absence of actual data.  
B. PADMANABHAMURTY, R. N. GUPTA
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Temperature gradient and heat source/sink impacts on triple-diffusive surface-tension-driven convection

Case Studies in Thermal Engineering
The impact of temperature gradients and internal heat sources/sinks on triple-diffusive surface-tension-driven (Marangoni) convection within a two-layer framework is analytically investigated using an exact solution methodology. A non-Darcy flow model is
Manjunatha Narayanappa, Vijaya Kumar, Sumithra Ramakrishna, Thabet Abdeljawad, Nabil Mlaiki   +4 more
doaj   +1 more source