Results 161 to 170 of about 2,359,207 (304)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Accurate Determination of the Temperature Sensitivity of UV-Induced Fiber Bragg Gratings. [PDF]

Sensors (Basel)
Cosme M, Pota M, Preizal J, Caldas P, Oliveira R, Nogueira R, Araújo FM, Cruz JL, Rego GM.   +8 more
europepmc   +1 more source

Temperature sensitivity of carbon concentrating mechanisms in the diatom Phaeodactylum tricornutum. [PDF]

Photosynth Res, 2023
Li M, Young JN.
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Rethinking the interpretation of spring phenological temperature sensitivity. [PDF]

NPJ Sci Plants
Walde MG, Vitasse Y, Wolkovich EM.
europepmc   +1 more source

Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products. [PDF]

Pharm Res, 2023
Kim JJ, Pritts JD, Ngo M, Estoll CR, Rao VA.   +4 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Harmonized global soil carbon and respiration datasets with derived turnover time and temperature sensitivity. [PDF]

Sci Data
Hashimoto S, Ito A, Nishina K.
europepmc   +1 more source

Using temperature sensitivity to estimate shiftable electricity demand. [PDF]

iScience, 2022
Roberts MJ, Zhang S, Yuan E, Jones J, Fripp M.   +4 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source