Results 141 to 150 of about 1,016,447 (267)

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Heterochromatin-based silencing of a foreign tandem repeat in Drosophila melanogaster shows unusual biochemistry and temperature sensitivity. [PDF]

Genetics
Gu T, Gracheva E, Lee M, Leung W, Bieser S, Nielsen A, Smiley AT, Vuong NNT, Walther M, Reuter G, Elgin SCR, Arsham AM.   +11 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Nitrate Availability Modulates the Temperature Sensitivity of N₂O and N₂ Production From Denitrification. [PDF]

Glob Chang Biol
Si Y, Trimmer M.
europepmc   +1 more source

Trends in Light and Temperature Sensitivity Recommendations among Licensed Biotechnology Drug Products. [PDF]

Pharm Res, 2023
Kim JJ, Pritts JD, Ngo M, Estoll CR, Rao VA.   +4 more
europepmc   +1 more source

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Probing millikelvin temperature sensitivity in chiral nanoparticles via optical forces. [PDF]

APL Mater
Im S, Hong W, Chandran GP, Wang X, Zhao Y.   +4 more
europepmc   +1 more source

Temperature Sensitivity of ¹⁴N-V and ¹⁵N-V Ground-State Manifolds. [PDF]

Phys Rev Appl, 2023
Lourette S, Jarmola A, Acosta VM, Birdwell AG, Budker D, Doherty MW, Ivanov T, Malinovsky VS.   +7 more
europepmc   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Temperature sensitivity analysis and service performance evaluation of aqueduct arch ring beam structures based on finite element method. [PDF]

Sci Rep
Chen W, Shen Z, Tang J, Jiang W, Fang B.
europepmc   +1 more source