Results 131 to 140 of about 16,749,992 (355)

Height‐Dependent Sensitivity of Cloud Scales to Surface Temperature Anomaly Observed by Active Satellites

open access: yesGeophysical Research Letters
As a key macrophysical property, cloud horizontal scale plays a critical role in cloud radiative effect (CRE), precipitation and convective structures.
Lijie Zhang   +7 more
doaj   +1 more source

THE EFFECT OF LOW TEMPERATURES ON THE SENSITIVITY OF RADIOMETERS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1930
The behavior of radiometers at low temperatures, besides being of some interest to the theoretical physicist,(2) is of considerable importance to one desiring to carry radiant energy measurements to an extreme limit. Various workers have already pushed the sensitivity of such instruments as the thermocouple, radio micrometer, and radiometer into the ...
openaire   +3 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Fiber Bragg grating pressure sensor with ultrahigh sensitivity and reduced temperature sensitivity

open access: yes, 2009
A fiber Bragg grating (FBG) pressure sensing scheme based on a flat diaphragm and an L-shaped lever is presented. An L-shaped lever transfers the pressure-induced defection of the flat diaphragm to the axial elongation of the FBG.
Zhang WT Chinese Acad Sci Inst Semicond Optoelect Syst Lab POB 912 Beijing 100083 Peoples R China. E-mail Address: zhangwt@semi.ac.cn   +3 more
core  

An Italian prospective multicenter survey on patients suspected of having non-celiac gluten sensitivity.

open access: yes, 2014
Background: Non-celiac gluten sensitivity (NCGS) is still an undefined syndrome with several unsettled issues despite the increasing awareness of its existence.
Bardella MT   +9 more
core   +1 more source

Water temperature modeling in the Garonne River (France) [PDF]

open access: yes, 2010
Stream water temperature is one of the most important parameters for water quality and ecosystem studies. Temperature can influence many chemical and biological processes and therefore impacts on the living conditions and distribution of aquatic ...
Larnier K.   +12 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Climate Warming Will Reduce Boreal Forest Litterfall, but the Response Differs Among Plant Functional Types

open access: yesEcology and Evolution
Boreal forests are critical carbon sinks increasingly threatened by climate change. More than two‐thirds of this boreal carbon is stored in soil and litter, highlighting the crucial role of litterfall for carbon and nutrient cycling.
Wai Phyo Thu   +4 more
doaj   +1 more source

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