Results 111 to 120 of about 1,113,211 (316)

The pricing of temperature futures at the Chicago Mercantile Exchange

open access: yes, 2010
This paper analyzes observed prices of US temperature futures at the Chicago Mercantile Exchange (CME). Results show that an index modeling approach without detrending captures the prices exceptionally well.
Wimmer, Maximilian, Dorfleitner, Gregor
core   +1 more source

Uncertainty of wheat water use: Simulated patterns and sensitivity to temperature and CO₂ [PDF]

open access: yes, 2016
Projected global warming and population growth will reduce future water availability for agriculture. Thus, it is essential to increase the efficiency in using water to ensure crop productivity. Quantifying crop water use (WU; i.e.
Ripoche, D   +158 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Heatwaves Suppress Isoprene Emission Optima in Subtropical Eucalyptus: Implications for Biogenic VOC Modeling Under Extreme Thermal Events

open access: yesGeophysical Research Letters
Isoprene emissions from tropical plants under moderate conditions are more temperature‐sensitive than temperate plants and current model predictions. However, the effect of extreme heatwaves on this sensitivity remains uncertain.
Jianqiang Zeng   +7 more
doaj   +1 more source

Exploring viscosity, polarity and temperature sensitivity of BODIPY-based molecular rotors

open access: yes, 2017
The sensitivity of structurally similar BODIPY-based molecular rotors to viscosity, temperature and solvent polarity was investigated.
Ismael López-Duarte   +19 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

High Pressure Enhances the Growth Rate of the Thermophilic Archaebacterium Methanococcus thermolithotrophicus without Extending Its Temperature Range

open access: yes, 1988
Temperature and hydrostatic pressure are essential in determining the assemblage of species in their specific biotopes. To evaluate the effect of high pressure on the range of viability of thermophiles, the pressure and temperature dependence of the ...
Lüdemann, Hans-Dietrich   +4 more
core   +1 more source

The "tipping" temperature within Subglacial Lake Ellsworth, West Antarctica and its implications for lake access. [PDF]

open access: yes, 2011
We present results from new geophysical data allowing modelling of the water flow within Subglacial Lake Ellsworth (SLE), West Antarctica. Our simulations indicate that this lake has a novel temperature distribution due to significantly thinner ice than ...
Woodward, J.   +19 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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