Results 121 to 130 of about 16,749,992 (355)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Cast composite solid propellants with different combustion stabilizers [PDF]

open access: yesScientific Technical Review, 2015
The effect of four different compounds as the combustion stabilizers of composite solid propellants based on the AP/HTPB/IPDI has been presented in this paper.
Rodić Vesna   +3 more
doaj  

Phase‐Sensitive Constant Temperature Anemometry

open access: yesMacromolecular Materials and Engineering, 2011
AbstractHot‐film measurements in bubbly flows provide time series that contain information about the liquid and the gas phase. Signal classification is required to disentangle the corresponding segments. The classification algorithms are prone to detection bias, which makes hot‐film measurements in two‐phase flows very difficult. We present a new phase‐
van den Berg, Thomas H.   +3 more
openaire   +4 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

In vivo comparative analysis of live influenza vaccine candidates obtained by reverse genetics and classical reassortment

open access: yesИнфекция и иммунитет
Difficulties identified in recent years while preparing reassortant live influenza vaccine (LAIV) strains related to the specific biological properties of currently circulating epidemic influenza viruses, necessitate the search for alternative ...
Natalie V. Larionova   +6 more
doaj   +1 more source

The pricing of temperature futures at the Chicago Mercantile Exchange [PDF]

open access: yes, 2010
This paper analyzes observed prices of US temperature futures at the Chicago Mercantile Exchange (CME). Results show that an index modeling approach without detrending captures the prices exceptionally well.
Wimmer, Maximilian, Dorfleitner, Gregor
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Atmospheric Feedbacks Reverse the Sensitivity of Modeled Photosynthesis to Stomatal Function

open access: yesJournal of Advances in Modeling Earth Systems
Stomata mediate fluxes of carbon and water between terrestrial plants and the atmosphere. These fluxes are governed by stomatal function and can be modulated in many Earth system models by an empirical parameter within the calculation of stomatal ...
Amy X. Liu   +14 more
doaj   +1 more source

Thermal Modeling of Temperature Distribution in Metal Additive Manufacturing Considering Effects of Build Layers, Latent Heat, and Temperature-Sensitivity of Material Properties

open access: yesJournal of Manufacturing and Materials Processing, 2018
A physics-based analytical model is proposed in order to predict the temperature profile during metal additive manufacturing (AM) processes, by considering the effects of temperature history in each layer, temperature-sensitivity of material properties ...
Elham Mirkoohi   +5 more
semanticscholar   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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