Results 91 to 100 of about 6,859,118 (305)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Ultra-high piezoelectric properties of BiFeO3–BaTiO3 lead-free piezoelectric ceramics enabled by a one-step sintering process

Journal of Advanced Ceramics
BiFeO3–BaTiO3 ceramics have been shown to possess considerable promise in the domain of high-temperature lead-free piezoelectric applications, a property attributable to their elevated Curie temperature and superior piezoelectric properties. However, the
Shiyuan Zhang, Xianxin Zhang, Jinhao Hu, Jinweng Tao, Yuanbing Wang, Huajun Sun, Ali Shoaib, Jing-Feng Li, Bo-Ping Zhang   +8 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Developmental stability in constant and fluctuating temperatures

Heredity, 1960
Uploaded by Plazi for TaxoDros. We do not have abstracts.
openaire   +1 more source

Stability of temperatures during hyperthermia treatments

International Journal of Hyperthermia, 1989
Attempts to develop a dosimetry for hyperthermia treatments have been limited by problems such as the inability of hyperthermia delivery systems to produce desired temperature distributions and the complexity of modelling complete temperature distributions.
M J, Engler, M W, Dewhirst, J R, Oleson
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Improving low-temperature activity of Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase [PDF]

, 2009
Sulfolobus acidocaldarius 2-keto-3-deoxygluconate aldolase (SacKdgA) displays optimal activity at 95 degrees C and is studied as a model enzyme for aldol condensation reactions.
Siemerink, M.A.J., Kengen, S.W.M., van der Oost, J., Kaper, T., Oost, J., van der, Perrakis, G., Wolterink-van Loo, S.   +6 more
core   +1 more source

Simultaneous achievement of large strain, low hysteresis, and high-temperature stability in textured BT-based piezoelectric ceramics

Journal of Advanced Ceramics
BaTiO3 (BT)-based piezoceramics with large temperature-stable strains and low hysteresis are urgently needed for high-precision actuators because of increasing environmental problems. Here, tetragonal [001]c-textured (Ba0.98Ca0.02)(Ti0.96Sn0.04)O3 (BCTS)
Xiyue Zhang, Zhe Wang, Peng Li, Yingchun Liu, Juan Du, Jigong Hao, Wei Li, Jiwei Zhai   +7 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source