Results 201 to 210 of about 1,206,514 (314)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Effect of Co-Dy Doping on Temperature Stability and Magnetic Properties of Nd-Fe-B Alloy: First-Principles and Characterization Analysis. [PDF]

ACS Omega
Zhao L, Zhou J, Liu Q, Yu Y, Li Z, Li M, Wang P.   +6 more
europepmc   +1 more source

Achieving Good Temperature Stability of Dielectric Constant by Constructing Composition Gradient in (Pb_1-x,La_x)(Zr_0.65,Ti_0.35)O₃ Multilayer Thin Films. [PDF]

Materials (Basel), 2022
Wu M, Xiao Y, Yan Y, Liu Y, Li H, Gao J, Zhong L, Lou X.   +7 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Conductive Hydrogel Motion Sensor with Low-Temperature Stability for Winter Sports and Sensing Rescue. [PDF]

Polymers (Basel)
Li W, Ming Y, Yang L, Ni Y, Chen Y, Xu W, Li L, Zheng C, Lin W.   +8 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Evaluating the Impact of the Wrapping Bag <i>TECOtherm Wrabbit</i> on Temperature Stability During Therapeutic Hypothermia Treatment of Hypoxic Ischemic Encephalopathy. [PDF]

Pediatr Discov
Katamesh R, Witt K, Ebert S.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Enhancing rotary dryer efficiency: Adjusting blower speed for optimal temperature stability in coffee bean drying. [PDF]

MethodsX
Syamsiana IN, Nafisah N, Suma ADW, Fiernaningsih N, Amalia RN, Nurwicaksana WA.   +5 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source