Results 101 to 110 of about 365,839 (309)

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Thermal Performance of Micro Hotplates with Novel Shapes Based on Single-Layer SiO2 Suspended Film

open access: yesMicromachines, 2018
In this paper, two kinds of suspended micro hotplate with novel shapes of multibeam structure and reticular structure are designed. These designs have a reliable mechanical strength, so they can be designed and fabricated on single-layer SiO2 suspended ...
Qi Liu   +3 more
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman   +9 more
wiley   +1 more source

Study on Temperature Field Uniformity of Dynamic Induction Heating for Camshaft of Marine Diesel Engine

open access: yesMachines
This paper focuses on the study of the induction heating process of a camshaft in a marine diesel engine. A three-dimensional finite element model for dynamic induction heating is established using the finite element method of multi-physical field ...
Xiaona Shi   +7 more
doaj   +1 more source

Research on Heat Transfer Characteristics of Vapor Chamber Integrated Heat Spreader for Chip Package

open access: yesZhileng xuebao, 2022
The high heat flux and the development of miniaturized chips have restricted the thermal diffusion ability of traditional metal materials. In this study, a vapor chamber with a micro-pin was designed and used in an integrated heat spreader (IHS).
Mao Chunlin   +5 more
doaj  

Functionally Graded Discs subjected to Uniform Temperature Loading

open access: yesScience and Engineering of Composite Materials, 2010
In this study, analytical stress analysis of annular rotating discs made of functionally graded materials (FGMs) subjected to uniform thermal loads were performed at different temperatures. The elasticity modulus and thermal expansion coefficient of the discs that has constant Poisson's ratio were assumed to vary radially according to power law ...
openaire   +6 more sources

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Thermal Management for a Stadium Power Supply Container Using a Rack-Level Air Cooling Strategy

open access: yesEnergies
This study investigates the airflow and thermal management of a compact electric energy storage system by using computational fluid dynamic (CFD) simulation. A porous medium model for predicting the flow resistance performance of the battery modules in a
Yue Dong   +5 more
doaj   +1 more source

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