Results 41 to 50 of about 115,907 (299)

The Role of Fresh Air Nozzle Orientation and Warehouse Dimensions in Modulating Airflow and Temperature in Pharmaceutical Warehouses: A Comparative Study [PDF]

AUT Journal of Mechanical Engineering
In this paper the results of parametric study and multi-objective optimization for the effect of fresh air inlet angle, warehouse height and shelves fullness on the flow and temperature distribution in the pharmaceutical warehouses is presented.
Hamed Safikhani, Somayeh Davoodabadi Farahani, Hadi Bagheri Haghighi   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Uniformalization of Temperature Field in Agitated Reactors.

Chemical engineering, 1970
パドル翼, アンカー翼, ゲート翼, ヘリカルリボン翼を持った撹拌反応槽でスチレンの塊状重合を行なわせて槽内の温度変化を測定した結果, ヘリカルリボン翼が温度の均一化に最良であることがわかった。また次元解析により新しい混合無次元数を導出し, 温度および濃度の均一化においてこの無次元数が撹拌翼の種類によらずほぼ一定値をとることを確かめた。最後に内部発熱のある場合の撹拌槽内の温度むらもまたこの混合無次元数に支配されることがわかった。
Tokuro Mizushina, Ryuzo Ito, Setsuro Hiraoka, Junkichi Watanabe   +3 more
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Growth Temperature Uniformity of MBE-Grown GaAs Determined by Scanning Room Temperature Photoluminescence [PDF]

, 1994
We have used scanning room temperature photoluminescence to map GaAs quantum well widthsand AIGaAs barrier compositions over 2-inch and 3-inch diameter epitaxial layers grown by MBE at temperatures ranging from 600 to 700ºC. Analysis of these maps allows
C. Choi-Feng, T. Bird, K. Stair, A. Moretti, F. Chambers   +4 more
core   +1 more source

Modeling and Analysis for Estimation of Junction Temperature Under Various Operating Conditions and Optimization of Pin-Fin Heat Sink for Automotive IGBT Modules

Applied Sciences
New energy vehicles (NEVs) rely heavily on Insulated-Gate Bipolar Transistors (IGBTs) to perform frequent battery voltage conversions for operations such as acceleration, deceleration, and hill climbing.
Chuncen Wu, Feng Wang, Yifan Song
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Optimization of Temperature Uniformity in Photovoltaic Laminators Based on Electromagnetic Induction Heating

Energies
To address the poor temperature uniformity of conventional heating systems in photovoltaic module laminators, this paper proposes an electromagnetic induction heating method incorporating temperature control. An electromagnetic–thermal coupling model was
Lei Shi, Yimai Liu, Pengju Duan, Liang Zhang, Aozhan Li   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Investigation on the Temperature Distribution Uniformity of an Extrusion-Based 3D Print Head and Its Temperature Control Strategy [PDF]

, 2022
Extrusion-based 3D printing for thermoplastic polymers manifests potential for the fabrication of biocompatible and biodegradable scaffolds. However, the uncontrollable shape of printed filaments usually negatively impacts on the printing processes.
Chen, Fangzheng, Lu, Lihua, Zhang, Peng, Qiang Gao, Fangzheng Chen, Gao, Qiang, Peng Zhang, Yu, Kaicheng, Lihua Lu, Kaicheng Yu   +9 more
core   +1 more source