Results 91 to 100 of about 3,586,880 (281)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Effective temperatures of hot Brownian motion
, 2014 We derive generalized Langevin equations for the translational and rotational motion of a heated Brownian particle from the fluctuating hydrodynamics of its non-isothermal solvent.
Falasco, G. +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Ab initio inspection of thermophysical experiments for molybdenum near melting
AIP Advances, 2018 We present quantum molecular dynamics calculations of thermophysical properties of solid and liquid molybdenum in the vicinity of melting. Detailed analysis of available experimental isobaric expansion data and extensive comparison over a wide set of ...
D. V. Minakov +2 more
doaj +1 more source
QCD Propagators at non-vanishing temperatures
, 2004 We investigate the behaviour of the gluon and ghost propagators, especially their infrared properties, at non-vanishing temperatures. To this end we solve their Dyson-Schwinger equations on a torus and find an infrared enhanced ghost propagator and an ...
A. Maas +9 more
core +2 more sources
Temperature-Sombor and Temperature-Nirmala Indices
INTERNATIONAL JOURNAL OF MATHEMATICS AND COMPUTER RESEARCH, 2022 In this paper, we introduce the temperature-Sombor index, modified temperature-Sombor index and temperature-Nirmala index of a graph. Also we compute these temperature indices for some standard graphs and tetrameric 1,3-adamantane. Furthermore, we establish some properties of newly defined temperature-Sombor index and temperature-Nirmala index.
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Shock and Release Temperatures in Molybdenum
, 2007 Shock and release temperatures in Mo were calculated, taking account of heating from plastic flow predicted using the Steinberg-Guinan model. Plastic flow was calculated self-consistently with the shock jump conditions: this is necessary for a rigorous ...
A. Seifter +10 more
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source