Results 101 to 110 of about 3,586,880 (281)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

The Influence of External Radiation on the Emission Properties of H- and He-like Argon Ions in High Temperature Plasma

Atoms
In the present work, the influence of external X-ray radiation on the kinetics of multicharged ions in high-temperature plasma is investigated. A generalized diagnostic approach is proposed for the electron density and temperature measurements of photo ...
Roman K. Kulikov, Igor Yu. Skobelev, Evgeny D. Filippov   +2 more
doaj   +1 more source

Quantum Simulators at Negative Absolute Temperatures

, 2012
We propose that negative absolute temperatures in ultracold atomic clouds in optical lattices can be used to simulate quantum systems in new regions of phase diagrams.
Rapp, Akos
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Local Kondo temperatures in atomic chains

, 2014
We study the effect of disorder in strongly interacting small atomic chains. Using the Kotliar- Ruckenstein slave-boson approach we diagonalize the Hamiltonian via scattering matrix theory.
Agundez, Ricardo, Blaauboer, Miriam, Rogge, Sven, Salfi, Joe   +3 more
core   +1 more source

Temperature oscillations [PDF]

Nature, 1992
Allen, M, Read, P, Smith, L
openaire   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Three-boson recombination at ultralow temperatures

, 2006
The effects of trimer continuum resonances are considered in the three-body recombination rate of a Bose system at finite energies for large and negative two-body scattering lengths ($a$).
Adhikari, Adhikari, Braaten, Braaten, Bringas, Efimov, Efimov, Efimov, Frederico, Jonsell, Kraemer, Lauro Tomio, M.T. Yamashita, Mohr, T. Frederico, Yamashita   +15 more
core   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Coulomb stable structures of charged dust particles in a dynamical trap at atmospheric pressure in air

New Journal of Physics, 2013
A mathematical simulation of a dust particle's behavior in the electrodynamic linear quadrupole trap with closing end electrodes allowed us to reveal several features of the phenomena.
L M Vasilyak, V I Vladimirov, L V Deputatova, D S Lapitsky, V I Molotkov, V Ya Pecherkin, V S Filinov, V E Fortov   +7 more
doaj   +1 more source