Results 51 to 60 of about 2,039,832 (291)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Milton Keynes Park Revisited: changes in internal temperatures [PDF]
27-30 April 2006 The Carbon Reduction in Buildings project has undertaken a pilot longitudinal survey based on a study of 160 ‘low-energy’ homes in 1989 in Milton Keynes Energy Park.
Lowe, R +5 more
core
Revising midlatitude summer temperatures back to A.D. 600 based on a wood density network [PDF]
Annually resolved and millennium-long reconstructions of large-scale temperature variability are primarily composed of tree ring width (TRW) chronologies.
Esper, J. +20 more
core +1 more source
The nonlinear dust-acoustic instability in the condensed submicron fraction of dust particles in the low-pressure glow discharge at ultra-low temperatures is experimentally and theoretically investigated.
Fedor M. Trukhachev +3 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Problems and prospects of Si3N4 materials for applications at temperatures above 1400 deg C
S.449-456Based on the understanding of the limiting mechanisms during service in structural applications at elevated temperatures, the potential of silicon nitride materials up to temperatures of 1500 deg C is discussed.
Herrmann, M. +3 more
core +1 more source
On the Possibility of Cross-Flow Vortex Cancellation by Plasma Actuators
Cancellation of the cross-flow vortices in a swept-wing boundary layer is attempted by plasma actuator array in numerical simulation. The response of the boundary layer to the stationary excitation by a single actuator section is measured experimentally ...
Amir Abdullaev +3 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source

