Results 31 to 40 of about 10,701 (237)

Development of Predictive Models for Tempering Behavior in Low-Carbon Bainitic Steel Using Integrated Tempering Parameters

Metals
Low-carbon bainitic steels are known for their excellent combination of strength and toughness, making them suitable for various industrial applications.
Guojin Sun, Qi Wang
doaj   +1 more source

Influence of Tempering Temperature on Performance of Roller Chain Isothermal Chain Plate

Jixie chuandong, 2022
The differences of microstructure and mechanical properties of 50CrVA chain plate caused by different tempering temperatures under the same isothermal quenching process and the same tempering holding time are analyzed，and the tensile and fatigue ...
Chen Jiang, Mengjiu Zhang, Zhaohua Shang, Ningning Pang   +3 more
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Revisiting rapid tempering of martensitic steel: the key role of tempering time over heating rate in carbide refinement and precipitation strengthening

Journal of Materials Research and Technology
Rapid tempering process can effectively improve the mechanical properties of martensitic steels such as strength, fracture toughness and impact toughness, which is mainly attributed to the promoted density and refined grain size of carbides. However, the
Baoqin Luo, Wenqi Mao, Yankang Zhao, Lijia Zhao, Hao Gao, Wenbin Ma, Shaolong Sheng, Nokeun Park, Pinaki Prasad Bhattacharjee, Qiang Wang   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Tempering behavior and mechanical properties of tempered AISI H13 steel

Materials Research Express
Microstructural evolutions of AISI H13 steel during tempering were quantitatively investigated by scanning electron microscopy (SEM), x-ray diffractometer (XRD), impact test machine, rockwell hardness tester, ball-on-disk tester in order to describe the ...
Gi-Hoon Kwon, Byoungho Choi, Young-Kook Lee, Kyoung Il Moon   +3 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Optimasi Parameter Quenching dan Tempering pada HRP Steel Lokal sebagai Baja Armor Nasional

Rekayasa Mesin, 2018
Armor steel is a high strength and hardness steel that used to protect against damage by an object, individual or vehicle from the direct pressure of projectile.
Yurianto Yurianto, Rudy Soenoko, Wahyono Soeprapto   +2 more
doaj   +1 more source