Results 41 to 50 of about 76,117 (295)

Robust Parameter Selection for Parallel Tempering [PDF]

, 2010
This paper describes an algorithm for selecting parameter values (e.g. temperature values) at which to measure equilibrium properties with Parallel Tempering Monte Carlo simulation.
FIRAS HAMZE, KAMRAN KARIMI, Katzgraber H. G., NEIL DICKSON   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Revisiting rapid tempering of martensitic steel: the key role of tempering time over heating rate in carbide refinement and precipitation strengthening

Journal of Materials Research and Technology
Rapid tempering process can effectively improve the mechanical properties of martensitic steels such as strength, fracture toughness and impact toughness, which is mainly attributed to the promoted density and refined grain size of carbides. However, the
Baoqin Luo, Wenqi Mao, Yankang Zhao, Lijia Zhao, Hao Gao, Wenbin Ma, Shaolong Sheng, Nokeun Park, Pinaki Prasad Bhattacharjee, Qiang Wang   +9 more
doaj   +1 more source

Temperance-Teaching [PDF]

Science, 1887
n ...
openaire   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Development of Predictive Models for Tempering Behavior in Low-Carbon Bainitic Steel Using Integrated Tempering Parameters

Metals
Low-carbon bainitic steels are known for their excellent combination of strength and toughness, making them suitable for various industrial applications.
Guojin Sun, Qi Wang
doaj   +1 more source

Simulated-tempering approach to spin-glass simulations

, 1994
After developing an appropriate iteration procedure for the determination of the parameters, the method of simulated tempering has been successfully applied to the 2D Ising spin glass.
A.M. Ferrenberg, B.A. Berg, B.A. Berg, B.A. Berg, B.A. Berg, E. Marinari, E. Marinari, H.F. Cheng, J.S. Wang, K. Binder, K.H. Fischer, M. Mezard, N. Metropolis, Peter Rehberg, R.N. Bhatt, W. Kerler, W.H. Press, Werner Kerler   +17 more
core   +1 more source

Approximate parameter inference in systems biology using gradient matching: a comparative evaluation [PDF]

, 2016
Background: A challenging problem in current systems biology is that of parameter inference in biological pathways expressed as coupled ordinary differential equations (ODEs).
Filippone, Maurizio, Husmeier, Dirk, Macdonald, Benn, Niu, Mu, Rogers, Simon   +4 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Tempering behavior and mechanical properties of tempered AISI H13 steel

Materials Research Express
Microstructural evolutions of AISI H13 steel during tempering were quantitatively investigated by scanning electron microscopy (SEM), x-ray diffractometer (XRD), impact test machine, rockwell hardness tester, ball-on-disk tester in order to describe the ...
Gi-Hoon Kwon, Byoungho Choi, Young-Kook Lee, Kyoung Il Moon   +3 more
doaj   +1 more source