Results 61 to 70 of about 10,467 (294)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Mechanical Properties of Tempered Nanobainite Steel [PDF]

open access: yesEngineering and Technology Journal, 2013
The mechanical properties of 62 SiMnCr 4 steel transformed isothermally at 280ºC for 5-hours were investigated. The hardness of nanobainite steel was equivalent to tempered martensite steel.
Dhafir S. Al-Fattal   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Weight-preserving simulated tempering [PDF]

open access: yes, 2020
Simulated tempering is a popular method of allowing MCMC algorithms to move between modes of a multimodal target density π . One problem with simulated tempering for multimodal targets is that the weights of the various modes change for different ...
Rosenthal, Jeffrey S.   +2 more
core   +1 more source

Effect of Heat Treatment on Mechanical Properties of 34CrNi3Mo Cast Steel

open access: yes工程科学与技术, 2012
: In order to research the effects of different heat treatment processes on mechanical properties of 34CrNi3Mo cast steel, the mechanical properties were compared in the condition of four kinds of heat treatment technologies which were “water ...
Wang De-fang, Yang Gang
doaj  

Microstructural evolution and mechanical properties of Cr–Ni–Mo–V steel with banded structure during tempering

open access: yesJournal of Alloys and Metallurgical Systems
Effects of tempering temperature on the microstructure evolution and mechanical properties of Cr–Ni–Mo–V steel with banded structure were investigated in this study.
Yunfei Du   +3 more
doaj   +1 more source

Effect of Heat Treatment Process on Properties of 9Ni Steel 5 mm Plate

open access: yesTeshugang, 2021
The effect of three kinds of process quenching + lamellarizing ( quenching from intercritical temperature) + tempering (QLT) , quenching + tempering( QT) , double normalizing + tempering ( NNT) on low temperature toughness of 5 mm 9Ni steel plate has ...
于雄, 徐伟, 刘洋
doaj  

Tempering Temperature Effects on Hardness and Impact Toughness of 56NiCrMo7 Steel [PDF]

open access: yes, 2011
Tempering Temperature Effects on Hardness and Impact Toughness of 56NiCrMo7 Steel The assessment of the effect of tempering temperature on hardness and impact toughness of a 56NiCrMo7 grade hot work tool steel was presented in the paper.
R. Dąbrowski, R. Dziurka
core   +1 more source

Effects of temperature, humidity, and diurnal temperature range on influenza incidence in a temperate region [PDF]

open access: yesInfluenza and Other Respiratory Viruses, 2019
AbstractBackgroundThe effect of temperature and humidity on the incidence of influenza may differ by climate region. In addition, the effect of diurnal temperature range on influenza incidence is unclear, according to previous study findings.ObjectivesThe aim of this study was to analyze the effects of temperature, humidity, and diurnal temperature ...
Ji‐Eun Park   +5 more
openaire   +2 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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