Results 181 to 190 of about 505,456 (287)

A Biodegradable Radical Polymer Enables High-Performance, Physically Transient Organic Memory. [PDF]

open access: yesAngew Chem Int Ed Engl
Ko J   +7 more
europepmc   +1 more source

Evolution of Prime Editing: Enhancing Efficiency and Expanding Capacity

open access: yesAdvanced Science, EarlyView.
Most rare diseases are caused by genetic mutations. Prime editing (PE) has emerged as a versatile tool capable of inducing diverse mutations without generating DNA double‐strand breaks. Despite its significant clinical potential, PE faces limitations in terms of efficiency and scalability.
Jihyeon Yu   +5 more
wiley   +1 more source

[Effect of an intervention in physical education classes on the reduction of sedentary behavior in adolescents]. [PDF]

open access: yesCad Saude Publica
Brito ALDS   +5 more
europepmc   +1 more source

Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics

open access: yesAdvanced Science, EarlyView.
Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi   +3 more
wiley   +1 more source

Post‐Translational Modifications in Animal Circadian Clocks

open access: yesAdvanced Science, EarlyView.
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley   +1 more source

3D‐Printed Aerogel Metamaterials with Multiple Heterogeneous Interfaces Enables Integrated Control of Microwave Field, Acoustic Field, and Thermal Field

open access: yesAdvanced Science, EarlyView.
The Direct‐Ink‐Writing (DIW) 3D‐printed aramid nanofibers (ANF)/carbon nanotubes (CNT)/liquid metal (LM) aerogel metamaterial demonstrates an effective and lightweight strategy to achieve polarization insensitive & ultra‐wideband microwave absorption from 2.65‐18 GHz, broadband noise reduction effect in the 2800‐6400 Hz and thermal suppression ...
Yijie Liu   +10 more
wiley   +1 more source

Spatial Control Over Tether‐Tunable Coordination on Palladium for Divergent Synthesis of Bicyclo[n.1.0]alkanes via Oxidative Cyclopropanation of Enynes

open access: yesAdvanced Science, EarlyView.
We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley   +1 more source

Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity

open access: yesAdvanced Science, EarlyView.
We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng   +15 more
wiley   +1 more source

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