Results 121 to 130 of about 3,361,719 (297)
Advanced Science, EarlyView.The formation of insulating Li2S during discharge in solid‐state lithium–sulfur batteries passivate reaction sites and limits sulfur utilization. In this work, a microstructure‐resolved modeling framework coupling transport and reaction kinetics is developed to predict charge–discharge behavior and reveal particle‐scale species evolution and incomplete
Arpan K. Sharma +4 more
wiley +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Soft, Flexible, and Stretchable Platforms for Tissue‐Interfaced Bioelectronics
Advanced Science, EarlyView.Bio‐integrated electronics provide mechanically compliant and stable interfaces with soft biological tissues. Representative applications include neural interfaces, wet‐organadhesive electronics, and skin‐interfaced devices. E represents Young´s modulus and ε represents strain.
Kento Yamagishi +3 more
wiley +1 more source
Post‐Translational Modifications in Animal Circadian Clocks
Advanced Science, EarlyView.Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley +1 more source
Advanced Science, EarlyView.The Direct‐Ink‐Writing (DIW) 3D‐printed aramid nanofibers (ANF)/carbon nanotubes (CNT)/liquid metal (LM) aerogel metamaterial demonstrates an effective and lightweight strategy to achieve polarization insensitive & ultra‐wideband microwave absorption from 2.65‐18 GHz, broadband noise reduction effect in the 2800‐6400 Hz and thermal suppression ...
Yijie Liu +10 more
wiley +1 more source
Advanced Science, EarlyView.We have developed a Pd‐catalyzed oxidative cyclopropanation of 1,n‐enynes employing cyclic diacyl peroxides as bifunctional reagents that serve as both tether‐tunable oxidants and spatially controlled dicarboxylate anions. ABSTRACT Bicyclo[n.1.0]alkanes are highly valuable scaffolds in drug discovery and synthetic chemistry.
Ting Yuan, Lei Shi
wiley +1 more source
Electrostatic Regulation of TEMPO Oxidation by Distal Molecular Charges
, 2020 Long Zhang, S. Ciampi, J. Gooding
semanticscholar +1 more source
Advanced Science, EarlyView.A polymer‐intercalated modulation assembly strategy was proposed to synthesize mesoporous single‐crystalline BiVO4 with tunable pore structure by co‐assembly of inorganic–organic composite through coordination bonds and hydrogen bonds. Thanks to single‐crystalline properties and mesoporous structure with vanadium vacancy microenvironment, the prepared ...
Wei Li +6 more
wiley +1 more source
Smart Optogenetics for Real‐Time Automated Control of Cardiac Electrical Activity
Advanced Science, EarlyView.We are able to stop dangerous heart‐rhythm spirals before they fully form. Within about 100 ms, it pinpoints the spiral's tiny central tip (≈0.9 mm) using light‐based sensing and machine learning, then shines targeted light to shut it down. This fast, precise, closed‐loop approach detects, targets, and terminates arrhythmias in real time.
Shanliang Deng +15 more
wiley +1 more source
Advanced Science, EarlyView.Difluoromethyl (CF2H) group, the bioisostere of hydroxyl thiol methyl or amide is privileged in medicinal chemistry due to hydrogen‐binding ability and lipophilic, metabolically stable, and chemical inert nature. However, enatioseleceive CF2H introduction remains challenging.
Peng Liu +9 more
wiley +1 more source