Results 1 to 10 of about 23,821 (111)
Cyclic voltammetry of some quinoxaline di-N-oxides and quinoxalines in dimethylformamide [PDF]
Electrochimica Acta, 1992 Abstract The first cathodic reductions of two series of substituted quinoxaline di- N -oxides and quinoxalines in dimethylformamide were measured. The effect of substituent on these reductions is reported and reversibility is discussed.
James R Ames
exaly +3 more sources
Regioselective Reaction of HeterocyclicN-Oxides, an Acyl Chloride, and Cyclic Thioethers [PDF]
The Journal of Organic Chemistry, 2018 Treatment of electron deficient pyridine N-oxides with 4-nitrobenzoyl chloride and a cyclic thioether in the presence of triethylamine leads to the corresponding 2-functionalized product in up to a 74% isolated yield. The transformation can also be accomplished with alternative nitrogen containing heterocycles, including quinolines, pyrimidines, and ...
Frei, Przemysslaw +6 more
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Regioselective Three-Component Reaction of Pyridine N-Oxides, Acyl Chlorides, and Cyclic Ethers [PDF]
Organic Letters, 2017 A novel three-component reaction of pyridine N-oxides, acyl chlorides, and cyclic ethers is described. Treatment of an electron-deficient pyridine N-oxide with an acyl chloride in the presence of a cyclic ether at 25-50 °C leads to a substituted pyridine as a single regioisomer in up to 58% isolated yield.
Jones, D. Heulyn +4 more
openaire +4 more sources
1,4-Di-N-oxide quinoxaline-2-carboxamide: Cyclic voltammetry and relationship between electrochemical behavior, structure and anti-tuberculosis activity [PDF]
Electrochimica Acta, 2011 To gain insight into the mechanism of action, the redox properties of 37 quinoxaline-2-carboxamide 1,4-di-N-oxides with varying degrees of anti-tuberculosis activity were studied in dimethylformamide (DMF) using cyclic voltammetry and first derivative cyclic voltammetry. For all compounds studied, electrochemical reduction in DMF is consistent with the
Aldana, I. (Ignacio) +8 more
openaire +2 more sources
Zeitschrift für Naturforschung B, 2006 The cyclization of a ribose-derived pentenose oxime with various halogen electrophiles showed bromine to be the most effective reagent, leading to 80% of L-lyxo/D-ribo-pyrroline N-oxides in an 84:16 diastereomeric ratio. In order to explore the scope of this facile process, several other γ,δ - unsaturated oximes were submitted to this reaction ...
Mahendra Gulla +4 more
openaire +1 more source
The FASEB Journal, 2008 TG100435 is a novel multi‐targeted Src family kinase inhibitor with demonstrated anticancer activity in preclinical species. Potent kinase inhibition is associated with TG100435 and its major N ‐oxide metabolite TG100855. The objectives of the current study were to identify the hepatic enzyme(
Ahmed A Kousba +3 more
openaire +1 more source
Chemical and Pharmaceutical Bulletin, 1984 The thermolysis of 1-methyl-2-vinylpiperidine N-oxide (13) resulted in Meisenheimer [1, 2] rearrangement to give the hexahydro-1, 2-oxazepine (23) and no [2, 3]-sigmatropic rearrangement product (24). Similarly, the 1-methyl-1, 2, 5, 6-tetrahydropyridine N-oxides (15), on heating, gave only the tetrahydro-1, 2-oxazepines (26, 27), together with the ...
SASHIDA, HARUKI, TSUCHIYA, TAKASHI
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Journal of Health Science, 2004 The aim of this study was to establish a preparation method needed to analyze the metabolites of an analytical procedure for antipsychotic phenothiazines and tertiary amino cyclic antidepressants by chemical reaction. These drugs were oxidized to their sulfoxide and N-oxide, respectively, with hydrogen peroxide using titanosilicate as the catalyst.
Ogamo, Akira, Fukumoto, Mariko
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Long-term stability of moisture-capturing hydrogels by preventing metal-mediated degradation. [PDF]
Nat CommunDíaz-Marín CD +10 more
europepmc +1 more source