Results 41 to 50 of about 14,027,089 (269)
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
International Journal of Electrochemical Science, 2019 Metal oxides have stimulated significant attention due to their potential applications in various technology and applications. In this paper, facile and novel hexagonal prism like zinc oxide (HP-ZnO) has been successfully synthesized by mechanochemical ...
Kesavan Ganesh +7 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Asymmetric N-oxidation catalyzed by bisguanidinium dinuclear oxodiperoxomolybdosulfate
Nature CommunicationsN-oxides play a pivotal role in natural products and emerging drug design, while also serving as valuable ligand scaffolds in organometallic chemistry. Among heteroatom oxidations, the conversion of amines to N-oxides is a critical and challenging facet.
Wentao Wu +7 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
International Journal of Electrochemical Science, 2017 In this work, binary metallic oxides of MnO2-Co3O4 nanocomposite was electrodeposited on graphene oxide (GO) modified electrode by a facile and one-step electrochemical method. The resultant MnO2-Co3O4/graphene (MnO2-Co3O4/GP) electrode was characterized
Su-Juan Li +5 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
, 2023 A straightforward cross-dehydrogenative coupling approach to incorporate alicyclic amino residues into the structure of model cyclic aldonitrones, 2H-imidazole oxides, is reported. The elaborated C(sp2)–H functionalization is achieved by employing cyclic
Oleg N. Chupakhin (1489117) +7 more
core +1 more source
Pyridine N-oxides as HAT reagents for photochemical C-H functionalization of electron-deficient heteroarenes [PDF]
, 2022 Pyridine N-oxides only recenly marked their presence in the photocatalysis outbreak, mainly serving as oxypyridinium salt precursors. Herein, their unique reactivity as a hydrogen atom transfer reagent in photochemical, Minisci-type alkylation of ...
Dorota, Gryko, Łukasz, Ciszewski
core +1 more source
The FASEB Journal, 2008 TG100435 is a novel multi‐targeted Src family kinase inhibitor with demonstrated anticancer activity in preclinical species. Potent kinase inhibition is associated with TG100435 and its major N ‐oxide metabolite TG100855. The objectives of the current study were to identify the hepatic enzyme(
Ahmed A Kousba +3 more
openaire +1 more source