Results 61 to 70 of about 81,546 (283)

Electrochemical Synthesis of a Binary Mn-Co Oxides Decorated Graphene Nanocomposites for Application in Nonenzymatic H2O2 Sensing

open access: yesInternational Journal of Electrochemical Science, 2017
In this work, binary metallic oxides of MnO2-Co3O4 nanocomposite was electrodeposited on graphene oxide (GO) modified electrode by a facile and one-step electrochemical method. The resultant MnO2-Co3O4/graphene (MnO2-Co3O4/GP) electrode was characterized
Su-Juan Li   +5 more
doaj   +1 more source

Cyclic Conversion of the Novel Src Kinase Inhibitor TG100435 and Its N‐Oxide Metabolite by Flavin‐Containing Monoxygenases and Cytochrome P450 Reductase

open access: yesThe FASEB Journal, 2008
TG100435 is a novel multi‐targeted Src family kinase inhibitor with demonstrated anticancer activity in preclinical species. Potent kinase inhibition is associated with TG100435 and its major N ‐oxide metabolite TG100855. The objectives of the current study were to identify the hepatic enzyme(
Ahmed A Kousba   +3 more
openaire   +1 more source

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

open access: yesFEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile   +8 more
wiley   +1 more source

Cyclic J integral using linear matching method [PDF]

open access: yes, 2012
The extended version of the latest Linear Matching Method (LMM) has the capability to evaluate the stable cyclic response, which produces cyclic stresses, residual stresses and plastic strain ranges for the low cycle fatigue assessment with cyclic load ...
Chen, Haofeng, Chen, Weihang
core  

Site-Specific Oxidative C–H Chalcogenation of (Hetero)Aryl-Fused Cyclic Amines Enabled by Nanocobalt Oxides [PDF]

open access: yes, 2018
By employing reusable nanocobalt oxides as the catalysts, a site-specific oxidative C–H chalcogenation of (hetero)­aryl-fused cyclic amines with various thiols and diselenides is presented for the first time.
Min Zhang   +11 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diversity and functional analysis of LuxR-type transcriptional regulators of cyclic lipopeptide biosynthesis in Pseudomonas fluorescens [PDF]

open access: yes, 2009
Cyclic lipopeptides (CLPs) are produced by many Pseudomonas species and have several biological functions, including a role in surface motility, biofilm formation, virulence, and antimicrobial activity.
Bruijn, I., de   +2 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Halogen‐Free Anisotropic Atomic‐Layer Etching of HfO2 at Room Temperature

open access: yesSmall Science
Hafnium(IV) oxide (HfO2)‐based materials have attracted substantial interest owing to their outstanding performance in advanced ultrathin semiconductor devices.
Shih‐Nan Hsiao   +5 more
doaj   +1 more source

Thermal rearrangements of cyclic amine ylides. IV. Rearrangement of .BETA.,.GAMMA.-unsaturated 1-alkylpiperidine N-oxides: Formation of 1,2-oxazepine derivatives.

open access: yesChemical and Pharmaceutical Bulletin, 1984
The thermolysis of 1-methyl-2-vinylpiperidine N-oxide (13) resulted in Meisenheimer [1, 2] rearrangement to give the hexahydro-1, 2-oxazepine (23) and no [2, 3]-sigmatropic rearrangement product (24). Similarly, the 1-methyl-1, 2, 5, 6-tetrahydropyridine N-oxides (15), on heating, gave only the tetrahydro-1, 2-oxazepines (26, 27), together with the ...
SASHIDA, HARUKI, TSUCHIYA, TAKASHI
openaire   +2 more sources

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