Results 31 to 40 of about 1,994,101 (341)

Predictive factors of quality of life in temporal and extratemporal lobe epilepsy: association with affective temperament profiles and psychiatric comorbidities

open access: yesArquivos de Neuro-Psiquiatria, 2021
Background: Investigating predictive factors of reduced quality of life (QOL) of patients and their association with focal epilepsy can improve management and treatment strategies.
Sehnaz Basaran, Halil İbrahim Tas
doaj   +1 more source

Magnetic resonance fingerprinting of temporal lobe white matter in mesial temporal lobe epilepsy

open access: yesAnnals of Clinical and Translational Neurology, 2019
Objective Mesial temporal lobe epilepsy (MTLE) is a network disorder. We aimed to quantify the white matter alterations in the temporal lobe of MTLE patients with hippocampal sclerosis (MTLE‐HS) by using magnetic resonance fingerprinting (MRF), a novel ...
Kang Wang   +8 more
doaj   +1 more source

Temporal lobe epilepsy and bipolar disorder: a case report

open access: yesPsychiatry and Behavioral Sciences, 2011
Temporal lobe epilepsy is a neuropsychiatric condition that can present with many psychiatric symptoms. Patients suffering from temporal lobe epilepsy may experience many cognitive, emotional, and behavioral problems between episodes leading to a need ...
Bulent Bahceci   +5 more
doaj   +1 more source

Interictal epileptiform discharges induce hippocampal-cortical coupling in temporal lobe epilepsy

open access: yesNature Medicine, 2016
Interactions between the hippocampus and the cortex are critical for memory. Interictal epileptiform discharges (IEDs) identify epileptic brain regions and can impair memory, but the mechanisms by which they interact with physiological patterns of ...
Jennifer N. Gelinas   +4 more
semanticscholar   +1 more source

Correlation Between Ictal Signs and Anatomical Subgroups in Temporal Lobe Seizures: A Stereoelectroencephalography Study

open access: yesFrontiers in Neurology, 2022
ObjectiveIctal semiology is a fundamental part of the presurgical evaluation of patients with temporal lobe epilepsy. We aimed to identify different anatomical and semiologic subgroups in temporal lobe seizures, and investigate the correlation between ...
Bo Zhang   +14 more
doaj   +1 more source

Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy

open access: yesNeural Regeneration Research, 2023
Cognitive impairment is the most common complication in patients with temporal lobe epilepsy with hippocampal sclerosis. There is no effective treatment for cognitive impairment.
Junzi Chen   +7 more
doaj   +1 more source

The Semantic Network at Work and Rest: Differential Connectivity of Anterior Temporal Lobe Subregions

open access: yesJournal of Neuroscience, 2016
The anterior temporal lobe (ATL) makes a critical contribution to semantic cognition. However, the functional connectivity of the ATL and the functional network underlying semantic cognition has not been elucidated.
R. Jackson   +3 more
semanticscholar   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao   +10 more
wiley   +1 more source

Differential medial temporal lobe and default-mode network functional connectivity and morphometric changes in Alzheimer's disease

open access: yesNeuroImage: Clinical, 2019
We report group level differential detection of medial temporal lobe resting-state functional connectivity disruption and morphometric changes in the transition from cognitively normal to early mild cognitive impairment in an age-, education- and gender ...
Kamil A. Grajski, Steven L. Bressler
doaj   +1 more source

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