Detection of temporal-lobe epilepsy with the physiological responses to fear and anxiety [PDF]
Epilepsy is a neurological disease caused by an abnormal neuronal activity on a region of the brain, which provokes seizures and the loss of consciousness to its patients. Epilepsy can be very disabling, since patients do not know when crisis or seizures
Perich Pallaruelo, Marta
core
Olfactory function in focal epilepsies: Understanding mesial temporal lobe epilepsy beyond the hippocampus [PDF]
Several lines of research have linked olfactory regions with the pathophysiology of focal epilepsies. Among those regions, the piriform cortex represents the major part of the primary olfactory cortex.
Aledo Serrano, Angel +6 more
core +2 more sources
Change over time in brain serotonin transporter binding in major depression: effects of therapy measured with [(123) I]-ADAM SPECT. [PDF]
Several studies have reported low brain serotonin transporter (SERT) binding in individuals with major depression. We hypothesized that the SERT standardized uptake ratio (SUR) values using [(123) I]-ADAM single photon emission computed tomography would ...
Amsterdam, Jay D +5 more
core +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Background: Intracranial dermoid cyst is a rare, benign, nonneoplastic tumor-like lesion that could cause seizures, headache, and hydrocephalus. We hypothesized that the temporal lobe dermoid cyst in combination with other factors were causing the ...
Keisuke Hatano +5 more
doaj +1 more source
Imaging memory in temporal lobe epilepsy: predicting the effects of temporal lobe resection [PDF]
Functional magnetic resonance imaging can demonstrate the functional anatomy of cognitive processes. In patients with refractory temporal lobe epilepsy, evaluation of preoperative verbal and visual memory function is important as anterior temporal lobe ...
Bonelli, S. B. +7 more
core
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Diffusion tensor tractography studies on mechanisms of recovery of injured fornix
The fornix, which connects the medial temporal lobe and the medial diencephalon, is involved in episodic memory as an important part of the Papez circuit.
Sung Ho Jang, Han Do Lee
doaj +1 more source
Memory reorganization following anterior temporal lobe resection: a longitudinal functional MRI study [PDF]
Anterior temporal lobe resection controls seizures in 50-60% of patients with intractable temporal lobe epilepsy but may impair memory function, typically verbal memory following left, and visual memory following right anterior temporal lobe resection ...
Bonelli, SB +8 more
core
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source

