Results 51 to 60 of about 369,446 (359)

Solving the Socratic Problem—A Contribution from Medicine [PDF]

open access: yes, 2018
This essay provides a medical theory that could clarify enigmas surrounding the historical Socrates. It offers textual evidence that Socrates had temporal lobe epilepsy and that its two types of seizure manifested as recurrent voices and peculiar ...
Muramoto, Osamu
core  

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

Association between temporal lobe P-glycoprotein expression and seizure recurrence after surgery for pharmacoresistant temporal lobe epilepsy

open access: yesNeurobiology of Disease, 2010
Surgery is recommended for pharmacoresistant temporal lobe epilepsy (TLE), but seizures recur in approximately one third of patients postsurgery.
Patrick Kwan   +9 more
doaj   +1 more source

Inhomogeneous cortical synchronization and partial epileptic seizures [PDF]

open access: yes, 2014
Objective: Interictal synchronization clusters have recently been described in several publications using diverse techniques, including neurophysiological recordings and fMRI, in patients suffering from epilepsy.
García de Sola, Rafael   +3 more
core   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin   +12 more
wiley   +1 more source

Temporal Lobe Epilepsy Etiological Classification

open access: yesPediatric Neurology Briefs, 1997
Clinical, EEG, and neuroimaging findings in a community-based cohort of 63 children with new-onset temporal lobe epilepsy (TLE) studied prospectively are reported from the Royal Children’s Hospital, Melbourne, Australia.
J Gordon Millichap
doaj   +1 more source

Neglecting the temporal lobe

open access: yesTrends in Cognitive Sciences, 2001
One of the first things today's student of cognitive neuroscience learns is the ‘what and where’ doctrine: the temporal lobe processes information about form whereas the parietal lobe processes information about space. This doctrine is strengthened by centuries of documented cases of hemispatial visual neglect – a deficit in spatial awareness thought ...
openaire   +3 more sources

Transsylvian selective amygdalohippocampectomy for treatment of medial temporal lobe epilepsy: Surgical technique and operative nuances to avoid complications [PDF]

open access: yes, 2014
Background: A number of different surgical techniques are effective for treatment of drug-resistant medial temporal lobe epilepsy. Of these, transsylvian selective amygdalohippocampectomy (SA), which was originally developed to maximize temporal lobe ...
Cohen-Gadol, Aaron A.   +2 more
core   +2 more sources

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez   +12 more
wiley   +1 more source

Temporal Lobe Epilepsy: Electroclinical Features

open access: yesPediatric Neurology Briefs, 1993
Results of video-EEG, PET, MRI, and pathological findings in 14 children aged 16 months to 12 years who were seizure-free after temporal lobectomy are reported in a multicenter, international study at Cleveland, Singapore, Naples, and Helsinki.
J Gordon Millichap
doaj   +1 more source

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