Results 71 to 80 of about 202,853 (306)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Aggression and temporal lobe epileptics : a correlational investigation among institutionalized subjects [PDF]
, 1980 This thesis explored the relationship between temporal lobe epilepsy and aggressive behavior. Prior studies have shown that temporal lobe epileptics display more aggressive behavior than do epileptics with other brain foci.
Otto, Terrance A.
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Neural Regeneration ResearchTemporal lobe epilepsy is a multifactorial neurological dysfunction syndrome that is refractory, resistant to antiepileptic drugs, and has a high recurrence rate.
Feng Chen +13 more
doaj +1 more source
Temporal Lobe Epilepsy: Electroclinical Features
Pediatric Neurology Briefs, 1993 Results of video-EEG, PET, MRI, and pathological findings in 14 children aged 16 months to 12 years who were seizure-free after temporal lobectomy are reported in a multicenter, international study at Cleveland, Singapore, Naples, and Helsinki.
J Gordon Millichap
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Recognition memory impairments in temporal lobe epilepsy: The contribution of recollection and metacognition [PDF]
, 2012 Temporal lobe epilepsy (TLE) is a complex neurological condition associated with a variety of memory problems. This thesis attempted to elucidate the nature and extent of memory impairments further in this clinical group by drawing on dual-process theory
Illman, Nathan Anthony
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Diffusion tensor tractography studies on mechanisms of recovery of injured fornix
Neural Regeneration Research, 2017 The fornix, which connects the medial temporal lobe and the medial diencephalon, is involved in episodic memory as an important part of the Papez circuit.
Sung Ho Jang, Han Do Lee
doaj +1 more source
Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs +7 more
wiley +1 more source
Characteristics of electroencephalography in neuropathic pain after spinal cord injury
Zhongguo kangfu lilun yu shijianObjective To investigate the electroencephalography (EEG) signal characteristics in patients with neuropathic pain (NP) associated with spinal cord injury (SCI).
LI Qiaozhen +7 more
doaj +1 more source
Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source