Results 91 to 100 of about 96,886 (299)

Familial Mesial Temporal Lobe Epilepsy

Pediatric Neurology Briefs, 2001
Clinical, genetic, and MR characteristics of 68 patients with familial mesial temporal lobe epilepsy (MTLE) were analysed at the University of Campinas-UNICAMP, Brazil.
J Gordon Millichap
doaj   +1 more source

Compulsive versifying after treatment of transient epileptic amnesia [PDF]

, 2015
Compulsive production of verse is an unusual form of hypergraphia that has been reported mainly in patients with right temporal lobe seizures. We present a patient with transient epileptic amnesia and a left temporal seizure focus, who developed isolated
Caine, D, Fletcher, PD, Massey, LA, Pasupathy, A, Rohrer, JD, Rossor, MN, Warren, JD, Woollacott, IO   +7 more
core  

Construction of pathogenic Sec16a mutation mouse model using CRISPR/Cas9

Animal Models and Experimental Medicine, EarlyView.
Yaqiang Hu et al. engineered a pathogenic Sec16a mutant mouse model using CRISPR/Cas9 technology. They observed that the Sec16a mutant mice displayed diminished learning and memory capabilities, along with a limb‐clasping phenotype upon tail suspension.
Yaqiang Hu, Zhiyang Zeng, Xinyu Ming, Shuming Yin, Yuting Guan, Liangcai Gao, Dali Li   +6 more
wiley   +1 more source

Interictal blood–brain barrier dysfunction in piriform cortex of people with epilepsy

Annals of Clinical and Translational Neurology
Objective The piriform cortex is considered to be highly epileptogenic. Its resection during epilepsy surgery is a predictor for postoperative seizure freedom in temporal lobe epilepsy. Epilepsy is associated with a dysfunction of the blood–brain barrier.
Freya Schulte, Johannes T. Reiter, Tobias Bauer, Julia Taube, Felix Bitzer, Juri‐Alexander Witt, Rory Piper, Anoja Thanabalasingam, Randi vonWrede, Attila Racz, Tobias Baumgartner, Valeri Borger, Louisa Specht‐Riemenschneider, Hartmut Vatter, Elke Hattingen, Ralf Deichmann, Christoph Helmstaedter, Alexander Radbruch, Alon Friedman, Rainer Surges, Theodor Rüber   +20 more
doaj   +1 more source

Temporal Lobe Epilepsy Etiological Classification

Pediatric Neurology Briefs, 1997
Clinical, EEG, and neuroimaging findings in a community-based cohort of 63 children with new-onset temporal lobe epilepsy (TLE) studied prospectively are reported from the Royal Children’s Hospital, Melbourne, Australia.
J Gordon Millichap
doaj   +1 more source

Predictors for surgical outcome in patients with Tumor-Associated epilepsy [PDF]

, 2017
This study aimed to evaluate possible predictors for postoperative outcome in patients with tumorassociated epilepsy. Methods: In this study, patients with tumor-associated epilepsy who were candidates for epilepsy surgery were included.
Badihian, Shervin., Barekatain, Majid., Basiratnia, Reza., Manuchehri, Navid., Mehvari-Habibabadi, AmirAli., Mehvari-Habibabadi, Jafar., Moein, Hooshang., Zaki, Bagher., Zare, Mohamad.   +8 more
core  

Epileptic high-frequency network activity in a model of non-lesional temporal lobe epilepsy [PDF]

, 2010
High-frequency cortical activity, particularly in the 250–600 Hz (fast ripple) band, has been implicated in playing a crucial role in epileptogenesis and seizure generation. Fast ripples are highly specific for the seizure initiation zone.
Cmejla, Roman, Finnerty, Gerald T, Jefferys, John G R, Jiruska, Premysl, Lofti, Noosheen, Powell, Andrew D   +5 more
core   +3 more sources

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeum Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Temporal Lobe Epilepsy: Electroclinical Features

Pediatric Neurology Briefs, 1993
Results of video-EEG, PET, MRI, and pathological findings in 14 children aged 16 months to 12 years who were seizure-free after temporal lobectomy are reported in a multicenter, international study at Cleveland, Singapore, Naples, and Helsinki.
J Gordon Millichap
doaj   +1 more source

Chronological Diagnostic Algorithm Predicting Neuropathology in Parkinsonism

Annals of Neurology, EarlyView.
Objective Pre‐mortem diagnosis of parkinsonism is often challenging due to atypical presentations, overlapping syndromes, and co‐pathologies. This study aimed to develop a machine learning‐based algorithm predicting neuropathology in parkinsonism using chronological clinical presentations, which has previously been underexplored.
Daisuke Ono, Hiroaki Sekiya, Alexia R. Maier, Neill R. Graff‐Radford, Zbigniew K. Wszolek, Dennis W. Dickson   +5 more
wiley   +1 more source