Results 81 to 90 of about 57,147 (307)

Histidine Supplementation Stabilizes Hearing and Vision and Improves Growth in HARS1‐Related Autosomal Recessive Disorder Associated With Usher‐Like Symptoms

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal recessive HARS1‐related disorder (originally described as Usher syndrome type 3B) caused by a homozygous Y454S variant in the histidyl‐tRNA synthetase gene (HARS1) is characterized by progressive sensorineural hearing and vision loss and respiratory deterioration with risk for sudden death following febrile illnesses.
Victoria Mok Siu, Rosan Kenana, Rana Chakrabarti, Sarah D. P. Wilhelm, Joseph Andrews, Susan J. Leat, Christina Parker, Michael Miller, Leslie A. Nangle, Wendy McCaul, Ashfia Chowdhury, Natalie Hutchings, Ryan A. Adams, Lauren Guy, Mandy Rhody, Verena Juncal, Marisa I. Mendes, Desiree E. C. Smith, Gajja S. Salomons, Angelica A. Moresco, Daphne L. McCulloch, D. Holmes Morton, Ilka U. Heinemann, C. Anthony Rupar   +23 more
wiley   +1 more source

Interictal blood–brain barrier dysfunction in piriform cortex of people with epilepsy

Annals of Clinical and Translational Neurology
Objective The piriform cortex is considered to be highly epileptogenic. Its resection during epilepsy surgery is a predictor for postoperative seizure freedom in temporal lobe epilepsy. Epilepsy is associated with a dysfunction of the blood–brain barrier.
Freya Schulte, Johannes T. Reiter, Tobias Bauer, Julia Taube, Felix Bitzer, Juri‐Alexander Witt, Rory Piper, Anoja Thanabalasingam, Randi vonWrede, Attila Racz, Tobias Baumgartner, Valeri Borger, Louisa Specht‐Riemenschneider, Hartmut Vatter, Elke Hattingen, Ralf Deichmann, Christoph Helmstaedter, Alexander Radbruch, Alon Friedman, Rainer Surges, Theodor Rüber   +20 more
doaj   +1 more source

Familial Mesial Temporal Lobe Epilepsy

Pediatric Neurology Briefs, 2001
Clinical, genetic, and MR characteristics of 68 patients with familial mesial temporal lobe epilepsy (MTLE) were analysed at the University of Campinas-UNICAMP, Brazil.
J Gordon Millichap
doaj   +1 more source

Epilepsy surgery around language cortex [PDF]

, 2009
Background. Both epilepsy surgery and surgery close to functionally significant cortical areas have challenged neurosurgeons in the last two decades.
Ribenis, Aksels
core  

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

Animal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee, Yoongeun Kim, Hyungjun Kim, Dae‐Hyun Hahm   +3 more
wiley   +1 more source

Temporal Lobe Epilepsy Etiological Classification

Pediatric Neurology Briefs, 1997
Clinical, EEG, and neuroimaging findings in a community-based cohort of 63 children with new-onset temporal lobe epilepsy (TLE) studied prospectively are reported from the Royal Children’s Hospital, Melbourne, Australia.
J Gordon Millichap
doaj   +1 more source

AI‐Driven Mapping of Seizure Spread Patterns

Annals of Neurology, EarlyView.
Objective The focus of epilepsy research has largely been on seizure onset; however, physicians typically examine the patterns of seizure spread past seizure onset as well. This study aims to align automated seizure analysis with clinical practice, leverage deep learning to standardize seizure annotations that varies among physicians, and understand ...
Andrew Y. Revell, Marc Jaskir, Akash R. Pattnaik, William K. S. Ojemann, Erin Conrad, Nishant Sinha, Brittany H. Scheid, Alfredo Lucas, John M. Bernabei, John Beckerle, Joel M. Stein, Sandhitsu R. Das, Brian Litt, Kathryn A. Davis   +13 more
wiley   +1 more source

Temporal Lobe Epilepsy: Electroclinical Features

Pediatric Neurology Briefs, 1993
Results of video-EEG, PET, MRI, and pathological findings in 14 children aged 16 months to 12 years who were seizure-free after temporal lobectomy are reported in a multicenter, international study at Cleveland, Singapore, Naples, and Helsinki.
J Gordon Millichap
doaj   +1 more source

Os motivos da baixa escolaridade são fatores preditores do desempenho cognitivo de pacientes adultos com epilepsia do lobo temporal mesial fármacorresistente? [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Ciências Médicas, Florianópolis, 2012Introdução: A escolaridade é positivamente associada com a performance cognitiva de pessoas ...
Cavallazzi, Gisele Genovez
core  

Déjà experiences in temporal lobe epilepsy [PDF]

, 2011
Historically, déjà vu has been linked to seizure activity in temporal lobe epilepsy, and clinical reports suggest that many patients experience the phenomenon as a manifestation of simple partial seizures.
Moulin, Chris JA, Butler, Chris R, Souchay, Celine, Illman, Nathan A   +3 more
core   +1 more source