Results 61 to 70 of about 57,147 (307)
Эпилепсия и пароксизмальные состояния, 2022 Background. Detected temporal lobe focal cortical dysplasia (FCD) often results in developing drug-resistant epilepsy requiring surgical treatment. In turn, temporal lobectomy, despite its high efficiency, can cause a certain deficit associated with ...
A. A. Sufianov +7 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Mesial temporal sclerosis presented with refractory seizure
APIK Journal of Internal Medicine, 2019 Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel +3 more
doaj +1 more source
Hippocampal sclerosis – cause or consequence of mesial temporal lobe epilepsy in children? [PDF]
Romanian Journal of Neurology, 2012 Mesial temporal lobe epilepsy with hippocampal sclerosis is a well defined epileptic syndromic entity, especially in adults. In pediatric population, this syndrome has been less well studied, probable because of the particular electroclinical features of
Adriana Gabriela Albeanu +3 more
doaj +1 more source
Temporal Lobe Epilepsy Semiology [PDF]
Epilepsy Research and Treatment, 2012 Epilepsy represents a multifaceted group of disorders divided into two broad categories, partial and generalized, based on the seizure onset zone. The identification of the neuroanatomic site of seizure onset depends on delineation of seizure semiology by a careful history together with video-EEG, and a variety of neuroimaging technologies such as MRI,
openaire +3 more sources
Regional thalamic neuropathology in patients with hippocampal sclerosis and epilepsy: A postmortem study [PDF]
, 2013 Purpose Clinical, experimental, and neuroimaging data all indicate that the thalamus is involved in the network of changes associated with temporal lobe epilepsy (TLE), particularly in association with hippocampal sclerosis (HS), with potential roles in ...
Martinian, L +3 more
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie +8 more
wiley +1 more source
Advanced Science, EarlyView.Neuronal PKM2‐driven glycolysis generates excess lactate that triggers histone H3K18 lactylation (H3K18la), establishing a pathogenic metabolic‐epigenetic axis in epilepsy. Elevated H3K18la enriches the Cop1 promoter, transcriptionally upregulating the E3 ubiquitin ligase COP1, which subsequently drives proteasomal degradation of GABAARβ2 and impairs ...
Yuan Meng +8 more
wiley +1 more source
Caspian Journal of Neurological Sciences, 2017 Background: Epilepsy is considered as one of the most important disorders in neurology. Temporal lobe epilepsy is a form of epilepsy including two main types of mesial and lateral (neocortex).
Jafar Mehvari +4 more
doaj
Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management
Advanced Science, EarlyView.ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak +9 more
wiley +1 more source