Results 71 to 80 of about 96,886 (299)

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich, Jonathan A. Gernert, Hanna Zimmermann, Lisa Tagnin, Marianthi Zeinaki, Laura Sanzo, Letizia Vogler, Elisabeth Kaufmann, Justina Dargvainiene, Frank Leypoldt, Gérard N. Bischof, Robert Perneczky, Boris‐Stephan Rauchmann, Simon Lindner, Günter U. Höglinger, Rudolf A. Werner, Martin Kerschensteiner, Tania Kümpfel, Matthias Brendel, Franziska S. Thaler   +19 more
wiley   +1 more source

The Sodium Channel B4-Subunits are Dysregulated in Temporal Lobe Epilepsy Drug-Resistant Patients [PDF]

, 2020
Temporal lobe epilepsy (TLE) is the most common type of partial epilepsy referred for surgery due to antiepileptic drug (AED) resistance. A common molecular target for many of these drugs is the voltage-gated sodium channel (VGSC).
Falciani, Francesco, Princivalle, Alessandra, Sheilabi, Mariam A., Sims, Edward J., Takeshita, Louise Y.   +4 more
core   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Mesial temporal sclerosis presented with refractory seizure

APIK Journal of Internal Medicine, 2019
Background: Refractory complex partial seizures are common in temporal lobe epilepsy, which is often associated with sclerosis of the structures of the medial temporal lobes, particularly the hippocampus.
Malav Patel, Rishika Reddy, Sangram Biradar, V H Kumarswamy   +3 more
doaj   +1 more source

Resection of dominant fusiform gyrus is associated with decline of naming function when temporal lobe epilepsy manifests after the age of five: A voxel-based lesion-symptom mapping study

NeuroImage: Clinical, 2022
Summary: Objective: To determine patients’ characteristics and regions in the temporal lobe where resections lead to a decline in picture naming. Methods: 311 patients with left hemispheric dominance for language were included who underwent epilepsy ...
Caroline Reindl, Anna-Lena Allgäuer, Benedict A. Kleiser, Müjgan Dogan Onugoren, Johannes D. Lang, Tamara M. Welte, Jenny Stritzelberger, Klemens Winder, Michael Schwarz, Stephanie Gollwitzer, Regina Trollmann, Julie Rösch, Arnd Doerfler, Karl Rössler, Sebastian Brandner, Dominik Madžar, Frank Seifert, Stefan Rampp, Hajo M. Hamer, Katrin Walther   +19 more
doaj   +1 more source

Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]

, 2015
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona, Diehl, Beate, Duncan, John S, Harper, Ronald M, Koepp, Matthias, Lhatoo, Samden, Micallef, Caroline, Sander, Josemir W, Scott, Catherine, Sisodiya, Sanjay M, Thom, Maria, Vos, Sjoerd B, Wandschneider, Britta   +12 more
core   +3 more sources

Persistent Bilateral [18F]THK5351 and Migrating Unilateral [18F]FDG Uptake in Anti‐LGI1 Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Anti–leucine‐rich glioma‐inactivated 1 encephalitis (LGI1‐E) can cause persistent cognitive deficits, but the mechanisms remain unclear. A 40‐year‐old woman with LGI1‐E presented with subacute cognitive deficits and showed mild left medial temporal lobe (MTL) swelling and fluid‐attenuated inversion recovery (FLAIR) hyperintensity on initial ...
Yusuke Akitomi, Kenichiro Taira, Masanori Kurihara, Kenji Ishibashi, Kenji Ishii, Fumio Suzuki, Aya Midori Tokumaru, Makoto Hara, Atsushi Iwata   +8 more
wiley   +1 more source

Hippocampal sclerosis – cause or consequence of mesial temporal lobe epilepsy in children? [PDF]

Romanian Journal of Neurology, 2012
Mesial temporal lobe epilepsy with hippocampal sclerosis is a well defined epileptic syndromic entity, especially in adults. In pediatric population, this syndrome has been less well studied, probable because of the particular electroclinical features of
Adriana Gabriela Albeanu, Sanda Magureanu, Dana Craiu, Lieven Lagae   +3 more
doaj   +1 more source

International Veterinary Epilepsy Task Force recommendations for a veterinary epilepsy-specific MRI protocol [PDF]

, 2015
Epilepsy is one of the most common chronic neurological diseases in veterinary practice. Magnetic resonance imaging (MRI) is regarded as an important diagnostic test to reach the diagnosis of idiopathic epilepsy.
A Bathen-Noethen, A Ciantis De, A Pakozdy, AA Raymond, AJ Hall, AK Shah, Akos Pakozdy, AM McIntosh, Andrea Fischer, Andrea Tipold, AR Deibler, CJ Abramson, Clare Rusbridge, DK Thompson, E Wagner, Edward E. Patterson, EJ Ives, EL So, F Cendes, F Rosenow, GS Berns, GS Berns, H Goldberg, Heidrun Potschka, Holger A. Volk, I Craven, J Laothamatas, J Oertzen Von, J Velmurugan, J Wellmer, J Wellmer, Jacques Penderis, Jelena Jovanovik, JS Duncan, JW Wheless, K Ono, Karen Muñana, Kaspar Matiasek, KL Stadler, KM Casey, KM Fiest, L Gygax, L Heske, L Kearsley-Fleet, LM Mellema, LS Garosi, Luisa De Risio, M Guye, M Konar, M Schwartz, Marjorie Milne, ME Milne, Mette Berendt, Michael Podell, MJ Fernandes, MS Anaya Garcia, N Farid, N Ogata, NK Focke, O Jacqmot, P Singh, P Szmuk, PF Cook, PM Smith, PT Wei, R Goncalves, R Kuzniecky, R Neppl, R Vasta, R Viitmaa, R Viitmaa, RA Thames, RL Wolf, Robyn G. Farqhuar, S Hecht, S Mizoguchi, S Torisu, Sam Long, SD Shorvon, Simon Platt, Sofie F. M. Bhatti, SP Knowler, T Guadalupe, T Hammen, T Kuwabara, TJ Oertzen von, TS Jokinen, U Ebert, V Jantti, V Martle, Veronika M. Stein, WD Gaillard, YM Lim, YS Ding, Z Haneef   +94 more
core   +6 more sources

The Tale of the Residual Tail: Insights From Continuous Intracranial Monitoring From Post‐Hippocampectomy Dynamics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Subtotal hippocampal resection can leave residual hippocampal tissue, yet the immediate postoperative electrophysiologic evolution of such remnants is unknown. We describe a patient with drug‐resistant temporal lobe epilepsy in whom a hippocampal remnant was continuously monitored using a responsive neurostimulator (RNS) following subtotal ...
Patrick Hartnett, Syeda Amrah Hashmi, Amaan Qureshi, Heather Spader, Shayan Moosa, Ifrah Zawar   +5 more
wiley   +1 more source