Results 11 to 20 of about 128,898 (315)

Mesial temporal lobe epilepsy with hippocampal sclerosis

open access: yesDefinitions, 2020
Mesial temporal lobe epilepsy with hippocampal sclerosis is a rare epilepsy syndrome defined by seizures originating in limbic areas of the mesial temporal lobe, particularly in the hippocampus, amygdala, and in the parahippocampal gyrus and its ...

semanticscholar   +1 more source

Characterizing the phenotype of drug-resistant childhood epilepsy associated with leukemia: A case series

open access: yesEpilepsy & Behavior Reports, 2021
Children with leukemia are at risk for epilepsy due to primary disease or neurotoxic therapies. We describe the phenotypes of drug-resistant epilepsy in 10 children with history of leukemia.Of 10 cases, 6 had features of Lennox-Gastaut syndrome, and 4 ...
Elham Abushanab   +2 more
doaj   +1 more source

Temporal Lobe Epilepsy Surgical Outcomes Can Be Inferred Based on Structural Connectome Hubs: A Machine Learning Study

open access: yesAnnals of Neurology, 2020
Medial temporal lobe epilepsy (TLE) is the most common form of medication‐resistant focal epilepsy in adults. Despite removal of medial temporal structures, more than one‐third of patients continue to have disabling seizures postoperatively.
E. Gleichgerrcht   +12 more
semanticscholar   +1 more source

Temporal plus epilepsy: the conception should be attack great importance and inquiring

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Mesial temporal lobe epilepsy (mTLE) is thought to be a network disease, most of them are medical intractable epilepsy. Surgery has benefit outcome, unfortunately, 20%-30% patients with mTLE who undergo surgery fail to achive seizure freedom.
WANG Wei⁃wei, WU Xun
doaj   +1 more source

A disinhibitory nigra-parafascicular pathway amplifies seizure in temporal lobe epilepsy

open access: yesNature Communications, 2020
The precise circuit of the substantia nigra pars reticulata (SNr) involved in temporal lobe epilepsy (TLE) is still unclear. Here we found that optogenetic or chemogenetic activation of SNr parvalbumin+ (PV) GABAergic neurons amplifies seizure activities
Bin Chen   +17 more
semanticscholar   +1 more source

Hippocampal neuron loss and astrogliosis in medial temporal lobe epileptic patients with mental disorders [PDF]

open access: yesJournal of Integrative Neuroscience, 2019
Hippocampal neuron loss and reactive astrogliosis are pathological features of medial temporal lobe epilepsy. Here, the expression of hippocampal astrogliosis-associated genes are studied in subjects with medial temporal lobe epilepsy and mental ...
Jun Lu, Hongxing Huang, Qichang Zeng, Xinmei Zhang, Min Xu, Yi Cai, Qin Wang, Yahui Huang, Qiong Peng, Lanqiuzi Deng
doaj   +1 more source

Atrophy and cognitive profiles in older adults with temporal lobe epilepsy are similar to mild cognitive impairment.

open access: yesBrain : a journal of neurology, 2020
Epilepsy incidence and prevalence peaks in older adults yet systematic studies of brain ageing and cognition in older adults with epilepsy remain limited. Here, we characterize patterns of cortical atrophy and cognitive impairment in 73 older adults with
E. Kaestner   +13 more
semanticscholar   +1 more source

Algebraic relationship between the structural network’s Laplacian and functional network’s adjacency matrix is preserved in temporal lobe epilepsy subjects

open access: yesNeuroImage, 2021
The relationship between anatomic and resting state functional connectivity of large-scale brain networks is a major focus of current research. In previous work, we introduced a model based on eigen decomposition of the Laplacian which predicts the ...
Farras Abdelnour   +4 more
doaj   +1 more source

Temporal lobe epilepsy and bipolar disorder: a case report

open access: yesPsychiatry and Behavioral Sciences, 2011
Temporal lobe epilepsy is a neuropsychiatric condition that can present with many psychiatric symptoms. Patients suffering from temporal lobe epilepsy may experience many cognitive, emotional, and behavioral problems between episodes leading to a need ...
Bulent Bahceci   +5 more
doaj   +1 more source

Frequency of Anxiety and Depression in Epileptic Patients

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Objectives: Depression and anxiety are commonly seen among epileptic patients. These comorbidities have a negative effect on achievement of effective treatment and improvement in the quality of life of epileptic patients.
Hakan Balibey   +3 more
doaj   +1 more source

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