Results 261 to 270 of about 107,776 (362)

Spontaneous Seizure Outcomes in Mice Using an Improved Version of the Pilocarpine Model of Temporal Lobe Epilepsy. [PDF]

Int J Mol Sci
Gaykema RP, Failor MJ, Maciejczuk A, Pikus M, Oliinyk M, Ellison MB, Behrooz AA, Singh K, Williamson JM, Perez-Reyes E.   +9 more
europepmc   +1 more source

A systematic review of brain health in adults with chronic pain

Anaesthesia, EarlyView.
Summary Introduction Recent research has linked chronic pain with an increased risk of clinical dementia diagnosis. Yet structural and functional brain changes associated with chronic pain and their potential role in accelerating brain ageing have not been characterised comprehensively.
Angeline Lee, Sara Al‐Dahwi, Thomas Angell, Abinaya Arulalagan, Ryan Bloxsom, Harry Clarkson, Rose Faure, Soutiam Goodarzi, Minshu Gupta, Adithya Kale, Kin Lam, Freyia Mahon‐Daly, Chloe Parry, Vidushi Pradhan, Finlay Ryan‐Phillips, Suraj Shah, Serina Sidhu, John Smiddy, Aparna Sridhar, Syed F. Tahmid, Robert Wight, Nia Roberts, Anya Topiwala   +22 more
wiley   +1 more source

Identification of Drug-Resistant Laterality in Bilateral Temporal Lobe Epilepsy. [PDF]

Cureus
Suzuki H, Mitsuhashi T, Iimura Y, Ueda T, Nishioka K, Nakajima M, Sugano H, Kondo A.   +7 more
europepmc   +1 more source

Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity

Brain Pathology, EarlyView.
Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen, Fei Yang, Wen‐Qian Yang, Ke Wang, Meng‐Shi Yang, Cheng Gou, Yan‐Ying Yu, Li‐Ling Chen, Ting‐Wan Xu, Dan Wang, Qian Wu, Qi‐Xin Zhou, Yan‐Bing Han   +12 more
wiley   +1 more source

Effective Connectivity Predicts Surgical Outcomes in Temporal Lobe Epilepsy: A SEEG Study. [PDF]

CNS Neurosci Ther
Hu X, Yao Y, Zhao B, Wang X, Li Z, Hu W, Zhang C, Zhang K.   +7 more
europepmc   +1 more source

Loss of Resting-State Posterior Cingulate Flexibility Is Associated with Memory Disturbance in Left Temporal Lobe Epilepsy

, 2015
Linda Douw, Catherine L. Leveroni, Naoaki Tanaka, Britt C. Emerton, Andrew Cole, Claus Reinsberger, Steven M. Stufflebeam   +6 more
openalex   +2 more sources

A complex network perspective on brain disease

Biological Reviews, EarlyView.
ABSTRACT If brain anatomy and dynamics have a complex network structure as it has become standard to posit, it is reasonable to assume that such a structure should play a key role not only in brain function but also in brain dysfunction. However, exactly how network structure is implicated in brain damage and whether at least some pathologies can be ...
David Papo, Javier M. Buldú
wiley   +1 more source

Comorbidities in the mouse model of temporal lobe epilepsy induced by intrahippocampal kainate. [PDF]

Epilepsia
Samalens L, Beets C, Courivaud C, Kahane P, Depaulis A.   +4 more
europepmc   +1 more source

Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations

Clinical Genetics, EarlyView.
Biallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Anees Muhammad, Mohammad Sadegh Shams Nosrati, Alireza Dostmohammadi, Reihaneh Khorasanian, Mariasavina Severino, Morteza Doustmohammadi, Francesca Madia, Siddharth Srivastava, Aisling Quinlan, Dario Paladini, Federico Zara, Marcello Scala   +11 more
wiley   +1 more source

Analysis of brain volume in hippocampal sclerotic temporal lobe epilepsy using automatic brain segmentation technology. [PDF]

Quant Imaging Med Surg
Li JQ, Li J, Zhang YL, Yan MN, Xiong YH, Song DY, Wang Z, Chen B.   +7 more
europepmc   +1 more source