Increased expression of matrix metalloproteinase-9 in patients with temporal lobe epilepsy [PDF]
Aim: The molecular mechanism of epileptogenesis in temporal lobe epilepsy is still unclear. Experimental studies have suggested that matrix metalloproteinases have important roles in this process, but human studies are limited.
Acar, Feridun +3 more
core +1 more source
A PIK3R2 Mutation in Familial Temporal Lobe Epilepsy as a Possible Pathogenic Variant
Temporal lobe epilepsy (TLE), the most common form of medically refractory focal epilepsy in adults, often requires surgery to alleviate seizures. By using next-generation sequencing, we identified a PIK3R2 mutation (NM_005027.4: c.265C > T; NP_005018.
Yishu Wang +8 more
doaj +1 more source
Temporal Lobe Surgery in Pediatric Patients: From Temporal Lobe Epilepsy to Temporal Plus Epilepsy [PDF]
Purpose Temporal lobe resection can be categorized as either temporal lobe epilepsy (TLE), which involves cortical resection confined to the temporal lobe, or temporal plus epilepsy (TPE), which entails temporal resection along with involvement of ...
Jun Chul Byun +4 more
doaj +1 more source
Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections [PDF]
Temporal lobe epilepsy, the most prevalent form of chronic focal epilepsy, is associated with a high prevalence of cognitive impairment but the responsible underlying pathological mechanisms are unknown.
Baxendale, S. +19 more
core +2 more sources
Preoperative automated fibre quantification predicts postoperative seizure outcome in temporal lobe epilepsy [PDF]
Approximately one in every two patients with pharmacoresistant temporal lobe epilepsy will not be rendered completely seizure-free after temporal lobe surgery. The reasons for this are unknown and are likely to be multifactorial.
Barker, GJ +9 more
core +2 more sources
Temporal Lobe Epilepsy and Autoimmunity
Epilepsy is one of the most frequent neurological diseases affecting quality of life in our country and in the world. Temporal lobe epilepsy is especially remarkable in terms of its frequency, resistance to treatment and large spectrum of the affected ...
Mine SEZGİN, Betül BAYKAN
doaj +1 more source
When is temporal lobe epilepsy not temporal lobe epilepsy? [PDF]
This scientific commentary refers to ‘Temporal plus epilepsy is a major determinant of temporal lobe surgery failures’, by Barba et al. . (doi:10.1093/brain/awv372). Stereotactic electroencephalography (SEEG) originated in France in the 1950s. Bancaud and Talairach, at St.
openaire +4 more sources
Temporal Lobe Epilepsy in Children [PDF]
The temporal lobe is a common focus for epilepsy. Temporal lobe epilepsy in infants and children differs from the relatively homogeneous syndrome seen in adults in several important clinical and pathological ways. Seizure semiology varies by age, and the ictal EEG pattern may be less clear cut than what is seen in adults.
Nickels, Katherine C. +3 more
openaire +2 more sources
Epilepsy is a common neurological condition with varied etiological causes, with temporal lobe epilepsy being the most common. Among the varied etiologies of temporal lobe epilepsy, mesial temporal sclerosis is an important one and it presents as ...
Prashanth Raghu +4 more
doaj +1 more source
Ictal verbal help-seeking: Occurrence and the underlying etiology. [PDF]
PURPOSE: Ictal verbal help-seeking has never been systematically studied before. In this study, we evaluated a series of patients with ictal verbal help-seeking to characterize its frequency and underlying etiology.
Aminian, Narsis +6 more
core +2 more sources

