Results 51 to 60 of about 580,857 (268)

Visual search in spatial neglect studied with a preview paradigm

Frontiers in Human Neuroscience, 2012
Impaired visual search is a hallmark of spatial neglect. When searching for a unique feature (e.g., colour) neglect patients often show only slight visual field asymmetries.
Julia eFellrath, Julia eFellrath, Vanessa eBlanche-Durbec, Armin eSchnider, Armin eSchnider, Anne-Sophie eJacquemoud, Radek ePtak, Radek ePtak   +7 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Moving stimuli facilitate synchronization but not temporal perception

Frontiers in Psychology, 2016
Recent studies have shown that a moving visual stimulus (e.g., a bouncing ball) facilitates synchronization compared to a static stimulus (e.g., a flashing light), and that it can even be as effective as an auditory beep. We asked a group of participants
Susana Silva, Sao Luis Castro
doaj   +1 more source

Project DyAdd: Non-linguistic Theories of Dyslexia Predict Intelligence

Frontiers in Human Neuroscience, 2020
Two themes have puzzled the research on developmental and learning disorders for decades. First, some of the risk and protective factors behind developmental challenges are suggested to be shared and some are suggested to be specific for a given ...
Marja Laasonen, Marja Laasonen, Pekka Lahti-Nuuttila, Pekka Lahti-Nuuttila, Sami Leppämäki, Pekka Tani, Jan Wikgren, Hanna Harno, Henna Oksanen-Hennah, Emmanuel Pothos, Axel Cleeremans, Matthew W. G. Dye, Denis Cousineau, Laura Hokkanen   +13 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Visualization Process of Temporal Data [PDF]

, 2004
Temporal data are abundantly present in many application domains such as banking, financial, clinical, geographical applications and so on. Temporal data have been extensively studied from data mining and database perspectives. Complementary to these studies, our work focuses on the visualization techniques of temporal data: a wide range of ...
Chaouki Daassi, Laurence Nigay, Marie-Christine Fauvet   +2 more
openaire   +2 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Maintenance Versus Transmission Deficits: The Effect of Delay on Naming Performance in Aphasia

Frontiers in Human Neuroscience, 2019
We propose that deficits in lexical retrieval can involve difficulty in transmission of activation between processing levels, or difficulty in maintaining activation.
Nadine Martin, Gary S. Dell
doaj   +1 more source