Results 61 to 70 of about 531,027 (318)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Temporal variation

, 1952
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Linear trends in seasonal vegetation time series and the modifiable temporal unit problem [PDF]

, 2012
Time series of vegetation indices (VI) derived from satellite imagery provide a consistent monitoring system for terrestrial plant productivity. They enable detection and quantification of gradual changes within the time frame covered, which are of ...
de Jong, R., S. de Bruin, Bruin, S., de, de Bruin, S, de Bruin, S., de Jong, Rogier, Jong, R., de, R. de Jong   +7 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Thermal imaging to detect spatial and temporal variation in the water status of grapevine (Vitis Vinifera L.)

, 2016
Thermal imaging can detect variation in stomatal conductance and therefore spatial variation in the water status of grapevine. Temporal variation can also be assessed, using indices that relate canopy temperature to reference temperatures, but, as yet ...
Grant, O.M., Baluja, J., Tardáguila, J. [0000-0002-6639-8723], Diago, M.P. [0000-0003-4049-0879], Ochagavía, H.   +4 more
core   +1 more source

Effect of Temporal Variation in Chemical Composition on Methane Yields of Rendering Plant Wastewater

, 2022
The effect of temporal variation in chemical composition on methane yields of rendering plant wastewater was studied in batch experiments at 37 °C.
Erika Conde, Prasad Kaparaju, Conde, Erika, Kaparaju, Prasad   +3 more
core   +1 more source

Global trends in the incidence and mortality of esophageal cancer from 1990 to 2017

Cancer Medicine, 2020
Background The incidence and mortality of esophageal cancer are high, with 5.90 new cases and 5.48 deaths per 100 000 people worldwide in 2017. The prognosis of esophageal cancer is poor, with an overall 5‐year survival rate of less than 20%.
Jiahui Fan, Zhenqiu Liu, Xianhua Mao, Xin Tong, Tiejun Zhang, Chen Suo, Xingdong Chen   +6 more
doaj   +1 more source